Comparison of endoscopic gastritis based on Kyoto classification between diffuse and intestinal gastric cancer.

Endoscopy Gastric cancer Gastritis Kyoto classification Lauren classification Pathology

Journal

World journal of gastrointestinal endoscopy
ISSN: 1948-5190
Titre abrégé: World J Gastrointest Endosc
Pays: United States
ID NLM: 101532474

Informations de publication

Date de publication:
16 May 2021
Historique:
received: 13 01 2021
revised: 14 02 2021
accepted: 14 04 2021
entrez: 28 5 2021
pubmed: 29 5 2021
medline: 29 5 2021
Statut: ppublish

Résumé

Gastric cancers can be categorized into diffuse- and intestinal-type cancers based on the Lauren histopathological classification. These two subtypes show distinct differences in metastasis frequency, treatment application, and prognosis. Therefore, accurately assessing the Lauren classification before treatment is crucial. However, studies on the gastritis endoscopy-based Kyoto classification have recently shown that endoscopic diagnosis has improved. To investigate patient characteristics including endoscopic gastritis associated with diffuse- and intestinal-type gastric cancers in Patients who underwent esophagogastroduodenoscopy at the Toyoshima Endoscopy Clinic were enrolled. The Kyoto classification included atrophy, intestinal metaplasia, enlarged folds, nodularity, and diffuse redness. The effects of age, sex, and Kyoto classification score on gastric cancer according to the Lauren classification were analyzed. We developed the Lauren predictive background score based on the coefficients of a logistic regression model using variables independently associated with the Lauren classification. Area under the receiver operative characteristic curve and diagnostic accuracy of this score were examined. A total of 499 Patient backgrounds, such as age, sex, endoscopic intestinal metaplasia, and endoscopic enlarged folds are useful for predicting the Lauren type of gastric cancer.

Sections du résumé

BACKGROUND BACKGROUND
Gastric cancers can be categorized into diffuse- and intestinal-type cancers based on the Lauren histopathological classification. These two subtypes show distinct differences in metastasis frequency, treatment application, and prognosis. Therefore, accurately assessing the Lauren classification before treatment is crucial. However, studies on the gastritis endoscopy-based Kyoto classification have recently shown that endoscopic diagnosis has improved.
AIM OBJECTIVE
To investigate patient characteristics including endoscopic gastritis associated with diffuse- and intestinal-type gastric cancers in
METHODS METHODS
Patients who underwent esophagogastroduodenoscopy at the Toyoshima Endoscopy Clinic were enrolled. The Kyoto classification included atrophy, intestinal metaplasia, enlarged folds, nodularity, and diffuse redness. The effects of age, sex, and Kyoto classification score on gastric cancer according to the Lauren classification were analyzed. We developed the Lauren predictive background score based on the coefficients of a logistic regression model using variables independently associated with the Lauren classification. Area under the receiver operative characteristic curve and diagnostic accuracy of this score were examined.
RESULTS RESULTS
A total of 499
CONCLUSION CONCLUSIONS
Patient backgrounds, such as age, sex, endoscopic intestinal metaplasia, and endoscopic enlarged folds are useful for predicting the Lauren type of gastric cancer.

Identifiants

pubmed: 34046150
doi: 10.4253/wjge.v13.i5.125
pmc: PMC8134854
doi:

Types de publication

Journal Article

Langues

eng

Pagination

125-136

Informations de copyright

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: All other authors have nothing to disclose.

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Auteurs

Osamu Toyoshima (O)

Department of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan. t@ichou.com.

Toshihiro Nishizawa (T)

Department of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan.

Shuntaro Yoshida (S)

Department of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan.

Tomonori Aoki (T)

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.

Fumiko Nagura (F)

Internal Medicine, Chitosefunabashi Ekimae Clinic, Tokyo 157-0054, Japan.

Kosuke Sakitani (K)

Department of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan.

Yosuke Tsuji (Y)

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.

Hayato Nakagawa (H)

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.

Hidekazu Suzuki (H)

Department of Gastroenterology and Hepatology, Tokai University School of Medicine, Isehara 259-1193, Japan.

Kazuhiko Koike (K)

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.

Classifications MeSH