SARS-CoV-2 variant B.1.1.7 susceptibility and infectiousness of children and adults deduced from investigations of childcare centre outbreaks, Germany, 2021.

B.1.1.7 COVID-19 SARS-CoV-2 VOC childcare centre infectiousness kindergarten outbreak secondary attack rate susceptibility

Journal

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452

Informations de publication

Date de publication:
05 2021
Historique:
entrez: 28 5 2021
pubmed: 29 5 2021
medline: 3 6 2021
Statut: ppublish

Résumé

We investigated three SARS-CoV-2 variant B.1.1.7 childcare centre and related household outbreaks. Despite group cohorting, cases occurred in almost all groups, i.e. also among persons without close contact. Children's secondary attack rates (SAR) were similar to adults (childcare centres: 23% vs 30%; p = 0.15; households: 32% vs 39%; p = 0.27); child- and adult-induced household outbreaks also led to similar SAR. With the advent of B.1.1.7, susceptibility and infectiousness of children and adults seem to converge. Public health measures should be revisited accordingly.

Identifiants

pubmed: 34047274
doi: 10.2807/1560-7917.ES.2021.26.21.2100433
pmc: PMC8161729
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

JAMA Pediatr. 2021 Feb 1;175(2):143-156
pubmed: 32975552
JAMA Netw Open. 2020 Dec 1;3(12):e2031756
pubmed: 33315116
PLoS One. 2020 Oct 8;15(10):e0240205
pubmed: 33031427
Lancet. 2020 Jun 27;395(10242):1973-1987
pubmed: 32497510
Lancet Infect Dis. 2020 Aug;20(8):920-928
pubmed: 32422201

Auteurs

Anna Loenenbach (A)

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.
These authors contributed equally to this article and share first authorship.

Inessa Markus (I)

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.
These authors contributed equally to this article and share first authorship.

Ann-Sophie Lehfeld (AS)

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.

Matthias An der Heiden (M)

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.

Walter Haas (W)

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.

Maya Kiegele (M)

Federal Office of Administration, Cologne, Germany.
Local Health Authority Bergstraße/Hesse, Heppenheim, Germany.

André Ponzi (A)

Federal Office of Administration, Cologne, Germany.
Local Health Authority Bergstraße/Hesse, Heppenheim, Germany.

Barbara Unger-Goldinger (B)

Local Health Authority Bergstraße/Hesse, Heppenheim, Germany.

Cornelius Weidenauer (C)

Local Health Authority Bergstraße/Hesse, Heppenheim, Germany.

Helen Schlosser (H)

Local Health Authority Bergstraße/Hesse, Heppenheim, Germany.

Alexander Beile (A)

Local Health Authority Bergstraße/Hesse, Heppenheim, Germany.

Udo Buchholz (U)

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.

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Classifications MeSH