N
Adenosine
/ analogs & derivatives
Animals
Apoptosis
Cell Differentiation
Cell Nucleus
/ genetics
Cell Proliferation
DNA Methylation
Female
Hematopoiesis
Humans
Leukemia, Myeloid, Acute
/ genetics
Liquid-Liquid Extraction
Mice
Mice, Inbred NOD
Mice, SCID
Nerve Tissue Proteins
/ genetics
Phase Transition
Proto-Oncogene Proteins c-myc
/ genetics
RNA Splicing Factors
/ genetics
RNA Stability
RNA, Messenger
/ chemistry
Tumor Cells, Cultured
Xenograft Model Antitumor Assays
RNA methylation
RNA-binding proteins
differentiation
myeloid leukemia
phase separation
Journal
Cancer cell
ISSN: 1878-3686
Titre abrégé: Cancer Cell
Pays: United States
ID NLM: 101130617
Informations de publication
Date de publication:
12 07 2021
12 07 2021
Historique:
received:
22
09
2020
revised:
22
03
2021
accepted:
28
04
2021
pubmed:
29
5
2021
medline:
21
12
2021
entrez:
28
5
2021
Statut:
ppublish
Résumé
N
Identifiants
pubmed: 34048709
pii: S1535-6108(21)00225-7
doi: 10.1016/j.ccell.2021.04.017
pmc: PMC8282764
mid: NIHMS1702256
pii:
doi:
Substances chimiques
Nerve Tissue Proteins
0
Proto-Oncogene Proteins c-myc
0
RNA Splicing Factors
0
RNA, Messenger
0
YTHDC1 protein, human
0
N-methyladenosine
CLE6G00625
Adenosine
K72T3FS567
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
958-972.e8Subventions
Organisme : NCI NIH HHS
ID : R01 CA186702
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA193842
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA225231
Pays : United States
Organisme : NINDS NIH HHS
ID : R35 NS111631
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK101989
Pays : United States
Organisme : NIDDK NIH HHS
ID : K01 DK084261
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL135564
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests S.R.J. is a scientific founder of Gotham Therapeutics and has equity in this company. D. J. P. is a consultant for Ventus Therapeutics. M.G.K. is a consultant for Accent Therapeutics and M.G.K.’s laboratory receives some financial support from 28-7. These disclosures are not directly related to these studies. There is a patent pending.
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