Chemoradiation Therapy as Definitive Treatment of Esophageal Cancer.


Journal

The Surgical clinics of North America
ISSN: 1558-3171
Titre abrégé: Surg Clin North Am
Pays: United States
ID NLM: 0074243

Informations de publication

Date de publication:
Jun 2021
Historique:
entrez: 28 5 2021
pubmed: 29 5 2021
medline: 8 6 2021
Statut: ppublish

Résumé

Definitive chemoradiation therapy avoids the perioperative and long-term morbidity of esophagectomy and is the standard of care for cervical esophageal cancer. There are significant differences in tumor response to chemoradiation and recurrence patterns between squamous cell cancer and adenocarcinoma of the esophagus. Multimodality therapy for esophageal cancer continues to progress, now with the widespread use of PET scanning and possible active surveillance in patients with complete clinical response to chemoradiation. As drug development and targeted therapy trials continue to expand, our understanding of tumor biology and precision medicine will continue to refine the treatment of esophageal cancer.

Identifiants

pubmed: 34048764
pii: S0039-6109(21)00018-9
doi: 10.1016/j.suc.2021.03.006
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

443-451

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Sue Xue Wang (SX)

Division of Thoracic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

M Blair Marshall (MB)

Division of Thoracic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA; Division of Thoracic Surgery, West Roxbury VA Medical Center, 1400 VFW Pkwy, West Roxbury, MA 02132, USA. Electronic address: mmarshall16@bwh.harvard.edu.

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Classifications MeSH