Randomized COVID-19 vaccination rollout can offer direct real-world evidence.
COVID-19
Evidence
Randomization
Routinely collected data
Study designs
Vaccines
Journal
Journal of clinical epidemiology
ISSN: 1878-5921
Titre abrégé: J Clin Epidemiol
Pays: United States
ID NLM: 8801383
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
31
03
2021
revised:
14
05
2021
accepted:
18
05
2021
pubmed:
29
5
2021
medline:
11
11
2021
entrez:
28
5
2021
Statut:
ppublish
Résumé
Vaccines are vital to control the Coronavirus disease 2019 (COVID-19) pandemic, but the pressure to quickly move from research to implementation in the context of a pandemic crisis raises concerns about benefits and harms, vaccine acceptance and fair access. Here we present a strategy for the COVID-19 vaccination rollout which can be rapidly embedded and would offer direct real-world evidence of vaccines on a large scale to generate otherwise unobtainable knowledge on the safety and perhaps efficacy of COVID-19 vaccines. Such strategic rollouts leveraging randomization can provide important evidence, for COVID-19 and in future occasions, for vaccines and beyond.
Identifiants
pubmed: 34048910
pii: S0895-4356(21)00160-8
doi: 10.1016/j.jclinepi.2021.05.014
pmc: PMC8146266
pii:
doi:
Substances chimiques
COVID-19 Vaccines
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
199-202Informations de copyright
Copyright © 2021. Published by Elsevier Inc.