Component Causes of Infectious Bovine Keratoconjunctivitis - The Role of Moraxella Species in the Epidemiology of Infectious Bovine Keratoconjunctivitis.
Genomics
Infectious bovine keratoconjunctivitis
MALDI-TOF MS
Moraxella bovis
Moraxella bovoculi
Moraxella ovis
Pathogenesis
Journal
The Veterinary clinics of North America. Food animal practice
ISSN: 1558-4240
Titre abrégé: Vet Clin North Am Food Anim Pract
Pays: United States
ID NLM: 8511905
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
entrez:
29
5
2021
pubmed:
30
5
2021
medline:
22
6
2021
Statut:
ppublish
Résumé
Infectious bovine keratoconjunctivitis (IBK) involves multiple factors and opportunistic pathogens, including members of the genus Moraxella, specifically M bovis. The causal role of M bovis is clear, where the presence of virulence factors that facilitate colonization (pili) and host cytotoxicity (RTX toxins) are well characterized, and IBK has been reproduced in many models. Experimental infection with M bovoculi has failed to reproduce IBK-typical lesions in cattle thus far. However, recent work using genomics and mass spectrometry have found genomic diversity and recombination within these species, making species differentiation complex and challenging the ability to assign IBK causality to these organisms.
Identifiants
pubmed: 34049659
pii: S0749-0720(21)00023-2
doi: 10.1016/j.cvfa.2021.03.004
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
279-293Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.