Component Causes of Infectious Bovine Keratoconjunctivitis - The Role of Moraxella Species in the Epidemiology of Infectious Bovine Keratoconjunctivitis.

Genomics Infectious bovine keratoconjunctivitis MALDI-TOF MS Moraxella bovis Moraxella bovoculi Moraxella ovis Pathogenesis

Journal

The Veterinary clinics of North America. Food animal practice
ISSN: 1558-4240
Titre abrégé: Vet Clin North Am Food Anim Pract
Pays: United States
ID NLM: 8511905

Informations de publication

Date de publication:
Jul 2021
Historique:
entrez: 29 5 2021
pubmed: 30 5 2021
medline: 22 6 2021
Statut: ppublish

Résumé

Infectious bovine keratoconjunctivitis (IBK) involves multiple factors and opportunistic pathogens, including members of the genus Moraxella, specifically M bovis. The causal role of M bovis is clear, where the presence of virulence factors that facilitate colonization (pili) and host cytotoxicity (RTX toxins) are well characterized, and IBK has been reproduced in many models. Experimental infection with M bovoculi has failed to reproduce IBK-typical lesions in cattle thus far. However, recent work using genomics and mass spectrometry have found genomic diversity and recombination within these species, making species differentiation complex and challenging the ability to assign IBK causality to these organisms.

Identifiants

pubmed: 34049659
pii: S0749-0720(21)00023-2
doi: 10.1016/j.cvfa.2021.03.004
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

279-293

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

John Dustin Loy (JD)

Nebraska Veterinary Diagnostic Center, School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, 4040 East Campus Loop North 115Q NVDC, Lincoln, NE 68583-0907, USA. Electronic address: jdloy@unl.edu.

Matthew Hille (M)

Nebraska Veterinary Diagnostic Center, School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, 4040 East Campus Loop North 115Q NVDC, Lincoln, NE 68583-0907, USA.

Gabriele Maier (G)

Department of Population Health & Reproduction, School of Veterinary Medicine, University of California Davis, 1 Shields Avenue, VM3B, Davis, CA 95616, USA.

Michael L Clawson (ML)

US Meat Animal Research Center, USDA Agriculture Research Service, Clay Center, 844 Road 313, Clay Center, NE 68933, USA.

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Classifications MeSH