Calculating estimated glomerular filtration rate without the race correction factor: Observations at a large academic medical system.


Journal

Clinica chimica acta; international journal of clinical chemistry
ISSN: 1873-3492
Titre abrégé: Clin Chim Acta
Pays: Netherlands
ID NLM: 1302422

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 12 04 2021
revised: 19 05 2021
accepted: 24 05 2021
pubmed: 31 5 2021
medline: 21 7 2021
entrez: 30 5 2021
Statut: ppublish

Résumé

Creatinine-based MDRD and CKD-EPI equations include a race correction factor, which results in higher eGFR in Black patients. We evaluated the impact on our patient population upon adoption of the CKD-EPI equation and the removal of the race correction factor from the equation. Retrospective analysis of blood creatinine results and respective eGFR values calculated by the MDRD or CKD-EPI equation without the race correction factor (CKD-EPI In our population, when changing from MDRD to CKD-EPI Changing from MDRD to CKD-EPI

Sections du résumé

BACKGROUND AND AIMS OBJECTIVE
Creatinine-based MDRD and CKD-EPI equations include a race correction factor, which results in higher eGFR in Black patients. We evaluated the impact on our patient population upon adoption of the CKD-EPI equation and the removal of the race correction factor from the equation.
MATERIALS AND METHODS METHODS
Retrospective analysis of blood creatinine results and respective eGFR values calculated by the MDRD or CKD-EPI equation without the race correction factor (CKD-EPI
RESULTS RESULTS
In our population, when changing from MDRD to CKD-EPI
CONCLUSIONS CONCLUSIONS
Changing from MDRD to CKD-EPI

Identifiants

pubmed: 34052206
pii: S0009-8981(21)00178-9
doi: 10.1016/j.cca.2021.05.022
pmc: PMC8286343
mid: NIHMS1709344
pii:
doi:

Substances chimiques

Creatinine AYI8EX34EU

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

16-22

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK017047
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Références

Am J Kidney Dis. 2014 May;63(5):713-35
pubmed: 24647050
Am Fam Physician. 2004 Sep 1;70(5):869-76
pubmed: 15368726
N Engl J Med. 2021 Feb 4;384(5):396-399
pubmed: 33406354
Clin Chem. 2006 Jan;52(1):5-18
pubmed: 16332993
N Engl J Med. 2006 Jun 8;354(23):2473-83
pubmed: 16760447
J Am Soc Nephrol. 2021 Jun 1;32(6):1305-1317
pubmed: 33837122
Nephron. 1976;16(1):31-41
pubmed: 1244564
N Engl J Med. 2020 Aug 27;383(9):874-882
pubmed: 32853499
J Gen Intern Med. 2021 Feb;36(2):464-471
pubmed: 33063202
Nephron Extra. 2012 Jan;2(1):293-302
pubmed: 23243414
Am Heart J. 2011 Sep;162(3):548-54
pubmed: 21884875
JAMA. 2019 Jul 9;322(2):113-114
pubmed: 31169890
Clin Chem. 2007 Apr;53(4):766-72
pubmed: 17332152
J Thorac Dis. 2016 Sep;8(9):E928-E931
pubmed: 27747028
J Appl Lab Med. 2018 Nov 1;3(3):366-377
pubmed: 33636914
J Am Soc Nephrol. 2011 Jan;22(1):147-55
pubmed: 21164029
Am J Kidney Dis. 2016 Nov;68(5):743-751
pubmed: 27555103
Ann Intern Med. 1999 Mar 16;130(6):461-70
pubmed: 10075613
Clin Chem. 2021 Mar 31;67(4):585-591
pubmed: 33686430
S Afr Med J. 2020 Feb 26;110(3):229-234
pubmed: 32657701
Hawaii J Med Public Health. 2015 Sep;74(9):302-10
pubmed: 26468426
N Engl J Med. 2012 Jul 5;367(1):20-9
pubmed: 22762315
Int J Nephrol. 2020 Jul 18;2020:2141038
pubmed: 32733708
Am J Kidney Dis. 1990 Sep;16(3):224-35
pubmed: 2205098
Kidney Int. 1973 Nov;4(5):346-9
pubmed: 4762581
J Am Soc Nephrol. 1993 Nov;4(5):1159-71
pubmed: 8305642
Kidney Int. 2019 May;95(5):1181-1189
pubmed: 30910379
Ann Intern Med. 2009 May 5;150(9):604-12
pubmed: 19414839
Am J Kidney Dis. 2008 Mar;51(3):395-406
pubmed: 18295055
J Am Soc Nephrol. 2007 Oct;18(10):2749-57
pubmed: 17855641

Auteurs

Junyan Shi (J)

Department of Laboratory Medicine and Pathology; University of Washington, School of Medicine, United States.

Edwin G Lindo (EG)

Department of Family Medicine; Department of Bioethics & Humanities; Office of Healthcare Equity; University of Washington, School of Medicine, United States.

Geoffrey S Baird (GS)

Department of Laboratory Medicine and Pathology; University of Washington, School of Medicine, United States.

Bessie Young (B)

Kidney Research Institute, Division of Nephrology, Department of Medicine; University of Washington, School of Medicine, United States.

Michael Ryan (M)

Division of Nephrology, Department of Medicine; University of Washington, School of Medicine, United States.

J Ashley Jefferson (JA)

Division of Nephrology, Department of Medicine; University of Washington, School of Medicine, United States.

Rajnish Mehrotra (R)

Kidney Research Institute, Division of Nephrology, Department of Medicine; University of Washington, School of Medicine, United States.

Patrick C Mathias (PC)

Department of Laboratory Medicine and Pathology; Department of Biomedical Informatics and Medical Education; University of Washington, School of Medicine, United States.

Andrew N Hoofnagle (AN)

Department of Laboratory Medicine and Pathology; Kidney Research Institute; Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine; University of Washington, School of Medicine, United States. Electronic address: ahoof@uw.edu.

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