Evaluation of open and minimally invasive spinal surgery for the treatment of thoracolumbar metastatic epidural spinal cord compression: a systematic review.

Corpectomy Metastasis Metastatic epidural spinal cord compression Minimally invasive spine Spine surgery Thoracolumbar

Journal

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
ISSN: 1432-0932
Titre abrégé: Eur Spine J
Pays: Germany
ID NLM: 9301980

Informations de publication

Date de publication:
10 2021
Historique:
received: 26 02 2021
accepted: 13 05 2021
pubmed: 31 5 2021
medline: 25 2 2023
entrez: 30 5 2021
Statut: ppublish

Résumé

Metastatic epidural spinal cord compression (MESCC) is a debilitating sequela of cancer that results in pain, disability, and neurologic deficits. Surgical techniques have included open surgical (OS) techniques with anterior and/or posterior decompression and fusion procedures. Further technical evolution has led to minimally invasive spinal (MIS) decompression and fusion. The objective of this study is to compare MIS to OS techniques in the treatment of thoracolumbar MESCC. A review of the literature was performed using PubMed database. Inclusion criteria included patients 18 years or older, thoracolumbar MESCC, and surgeries with instrumented fusion. A total of 451 articles met the inclusion criteria and further analysis narrowed them down to 81 articles. Variables collected included blood loss, length of stay, operative time, pre- and postoperative Frankel grade, and complications. A total of 5726 papers were collected, with a total of 81 papers meeting final inclusion criteria: 26 papers with MIS technique and 55 with OS. A total of 2267 patients were evaluated. They were split into three surgical subtypes of MIS and OS: posterior decompression and fusion, partial corpectomy, and complete corpectomy. Overall, MIS had lower operative time, blood loss, and complications compared to OS. A timeline analysis showed reduction of complication rates in MIS surgery between papers published over a 28-year period. MESCC carries significant morbidity and mortality. Surgical approaches for palliative treatment should account for this fact. We conclude that MIS techniques offer a viable alternative to traditional OS approaches with lower overall morbidity and complications.

Sections du résumé

BACKGROUND
Metastatic epidural spinal cord compression (MESCC) is a debilitating sequela of cancer that results in pain, disability, and neurologic deficits. Surgical techniques have included open surgical (OS) techniques with anterior and/or posterior decompression and fusion procedures. Further technical evolution has led to minimally invasive spinal (MIS) decompression and fusion. The objective of this study is to compare MIS to OS techniques in the treatment of thoracolumbar MESCC.
METHODS
A review of the literature was performed using PubMed database. Inclusion criteria included patients 18 years or older, thoracolumbar MESCC, and surgeries with instrumented fusion. A total of 451 articles met the inclusion criteria and further analysis narrowed them down to 81 articles. Variables collected included blood loss, length of stay, operative time, pre- and postoperative Frankel grade, and complications.
RESULTS
A total of 5726 papers were collected, with a total of 81 papers meeting final inclusion criteria: 26 papers with MIS technique and 55 with OS. A total of 2267 patients were evaluated. They were split into three surgical subtypes of MIS and OS: posterior decompression and fusion, partial corpectomy, and complete corpectomy. Overall, MIS had lower operative time, blood loss, and complications compared to OS. A timeline analysis showed reduction of complication rates in MIS surgery between papers published over a 28-year period.
CONCLUSION
MESCC carries significant morbidity and mortality. Surgical approaches for palliative treatment should account for this fact. We conclude that MIS techniques offer a viable alternative to traditional OS approaches with lower overall morbidity and complications.

Identifiants

pubmed: 34052895
doi: 10.1007/s00586-021-06880-7
pii: 10.1007/s00586-021-06880-7
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2906-2914

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Mohammed Alshareef (M)

Department of Neurological Surgery, Medical University of South Carolina, Charleston, SC, 301 CSB, USA.
Department of Neurooncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

Gibson Klapthor (G)

Department of Radiology, Wake Forest University, Winston-Salem, NC, USA.
Department of Neurooncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

Ali Alawieh (A)

Department of Neurosurgery, Emory University, Atlanta, GA, USA.
Department of Neurooncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

Stephen Lowe (S)

Department of Neurological Surgery, Medical University of South Carolina, Charleston, SC, 301 CSB, USA.
Department of Neurooncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

Bruce Frankel (B)

Department of Neurological Surgery, Medical University of South Carolina, Charleston, SC, 301 CSB, USA. frankel@musc.edu.
Department of Neurooncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA. frankel@musc.edu.

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