Recent advances in gene therapy for atrial fibrillation.
atrial fibrillation
gene therapy
Journal
Journal of cardiovascular electrophysiology
ISSN: 1540-8167
Titre abrégé: J Cardiovasc Electrophysiol
Pays: United States
ID NLM: 9010756
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
revised:
17
05
2021
received:
02
03
2021
accepted:
24
05
2021
pubmed:
31
5
2021
medline:
21
10
2021
entrez:
30
5
2021
Statut:
ppublish
Résumé
Atrial fibrillation (AF) is the most common heart rhythm disorder in adults and a major cause of stroke. Unfortunately, current treatments for AF are suboptimal as they are not targeting the molecular mechanisms underlying AF. In this regard, gene therapy is emerging as a promising approach for mechanism-based treatment of AF. In this review, we summarize recent advances and challenges in gene therapy for this important cardiovascular disease.
Identifiants
pubmed: 34053133
doi: 10.1111/jce.15116
pmc: PMC9281901
mid: NIHMS1820429
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2854-2864Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL125881
Pays : United States
Organisme : NHLBI NIH HHS
ID : RA: R01 HL093490
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL093490
Pays : United States
Organisme : American Heart Association-American Stroke Association
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL140061
Pays : United States
Informations de copyright
© 2021 Wiley Periodicals LLC.
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