A systematic review and meta-analysis of the Endometriosis and Mental-Health Sequelae; The ELEMI Project.

Cross-Sectional Studies Dysmenorrhea Dyspareunia Endometriosis / complications Female Humans Mental Health Pelvic Pain / epidemiology
BAME adenomyosis chronic pelvic pain dysmenorrhea dyspareunia endometriosis mental health women’s health women’s mental health

Journal

Women's health (London, England)
ISSN: 1745-5065
Titre abrégé: Womens Health (Lond)
Pays: United States
ID NLM: 101271249

Informations de publication

Date de publication:
Historique:
entrez: 31 5 2021
pubmed: 1 6 2021
medline: 29 10 2021
Statut: ppublish

Résumé

It is important to evaluate sequalae for complex chronic health conditions such as endometriosis and mental health disorders. Endometriosis impacts 1 in 10 women. Mental health outcomes can be a primary determinant in many physical health conditions although this is an area not well researched particularly in women's health. This has been problematic for endometriosis patients in particular, who report mental health issues as well as other key comorbidities such as chronic pelvic pain and infertility. This could be partly due to the complexities associated with comprehensively exploring overlaps between physical and mental health disorders in the presence of multiple comorbidities and their potential mechanistic relationship. In this evidence synthesis, a systematic methodology and mixed-methods approaches were used to synthesize both qualitative and quantitative data to examine the prevalence of the overlapping sequalae between endometriosis and psychiatric symptoms and disorders. As part of this, an evidence synthesis protocol was developed which included a systematic review protocol that was published on PROSPERO (CRD42020181495). The aim was to identify and evaluate mental health reported outcomes and prevalence of symptoms and psychiatric disorders associated with endometriosis. A total of 34 papers were included in the systematic review and 15 were included in the meta-analysis. Anxiety and depression symptoms were the most commonly reported mental health outcomes while a pooled analysis also revealed high prevalence of chronic pelvic pain and dyspareunia. It is evident that small-scale cross-sectional studies have been conducted in a variety of settings to determine mental health outcomes among endometriosis patients. Further research is required to comprehensively evaluate the mental health sequalae with endometriosis.

Sections du résumé

BACKGROUND
It is important to evaluate sequalae for complex chronic health conditions such as endometriosis and mental health disorders. Endometriosis impacts 1 in 10 women. Mental health outcomes can be a primary determinant in many physical health conditions although this is an area not well researched particularly in women's health. This has been problematic for endometriosis patients in particular, who report mental health issues as well as other key comorbidities such as chronic pelvic pain and infertility. This could be partly due to the complexities associated with comprehensively exploring overlaps between physical and mental health disorders in the presence of multiple comorbidities and their potential mechanistic relationship.
METHODS
In this evidence synthesis, a systematic methodology and mixed-methods approaches were used to synthesize both qualitative and quantitative data to examine the prevalence of the overlapping sequalae between endometriosis and psychiatric symptoms and disorders. As part of this, an evidence synthesis protocol was developed which included a systematic review protocol that was published on PROSPERO (CRD42020181495). The aim was to identify and evaluate mental health reported outcomes and prevalence of symptoms and psychiatric disorders associated with endometriosis.
FINDINGS
A total of 34 papers were included in the systematic review and 15 were included in the meta-analysis. Anxiety and depression symptoms were the most commonly reported mental health outcomes while a pooled analysis also revealed high prevalence of chronic pelvic pain and dyspareunia.
INTERPRETATION
It is evident that small-scale cross-sectional studies have been conducted in a variety of settings to determine mental health outcomes among endometriosis patients. Further research is required to comprehensively evaluate the mental health sequalae with endometriosis.

Identifiants

DOI: 10.1177/17455065211019717 PMID: 34053382 PMC: PMC8182632
pubmed: 34053382
doi: 10.1177/17455065211019717
pmc: PMC8182632
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

17455065211019717

Références

Int J Clin Pract. 2009 May;63(5):707-11
pubmed: 19392920
Soc Sci Med. 2017 Dec;195:42-49
pubmed: 29132081
J Sex Marital Ther. 2002 Jul-Sep;28(4):317-30
pubmed: 12082670
Fertil Steril. 2011 Aug;96(2):366-373.e8
pubmed: 21718982
J Pain Res. 2016 Nov 16;9:1049-1056
pubmed: 27895510
Obstet Gynecol. 2016 Jun;127(6):1045-1053
pubmed: 27159755
Am J Pathol. 1927 Mar;3(2):93-110.43
pubmed: 19969738
Hum Reprod. 2017 Aug 1;32(8):1667-1673
pubmed: 28637285
Hum Reprod. 2012 May;27(5):1292-9
pubmed: 22422778
Health (London). 2020 Jan;24(1):79-93
pubmed: 29978723
Annu Rev Physiol. 2011;73:163-82
pubmed: 21054165
Biol Reprod. 2018 Aug 1;99(2):349-359
pubmed: 29425272
J Psychosom Res. 1993;37(2):111-6
pubmed: 8463987
Fertil Steril. 2007 Oct;88(4):795-803
pubmed: 17451690
Sex Med. 2020 Jun;8(2):274-281
pubmed: 32061579
Hum Reprod. 2016 Nov;31(11):2577-2586
pubmed: 27619771
BJOG. 2008 Oct;115(11):1382-91
pubmed: 18715240
Stress. 2008 Sep;11(5):390-7
pubmed: 18800310
Fertil Steril. 2011 Jul;96(1):107-12
pubmed: 21621771
J Affect Disord. 2017 Jan 15;208:672-673
pubmed: 27451810
J Lab Physicians. 2010 Jan;2(1):1-9
pubmed: 21814398
Best Pract Res Clin Obstet Gynaecol. 2018 Jul;50:2-10
pubmed: 29545113
JAMA. 2002 Nov 20;288(19):2469-75
pubmed: 12435261
Biomed Res Int. 2014;2014:786830
pubmed: 25045701
Clin Obstet Gynecol. 2019 Mar;62(1):22-36
pubmed: 30383545
JAMA Psychiatry. 2016 Nov 1;73(11):1154-1162
pubmed: 27680324
F1000Res. 2019 Apr 23;8:
pubmed: 31069056
J Reprod Med. 2004 Feb;49(2):115-20
pubmed: 15018440
Obstet Gynecol. 1984 Aug;64(2):151-4
pubmed: 6234483
Int J Environ Res Public Health. 2020 May 21;17(10):
pubmed: 32455821
J Obstet Gynaecol Can. 2015 Nov;37(11):1006-15
pubmed: 26629721
J Sex Marital Ther. 2000 Apr-Jun;26(2):191-208
pubmed: 10782451
Fertil Steril. 1995 Apr;63(4):796-800
pubmed: 7890065
J Affect Disord. 2016 Jan 15;190:282-285
pubmed: 26544610
Fertil Steril. 2019 Feb;111(2):327-340
pubmed: 30527836
J Sex Med. 2011 Feb;8(2):497-503
pubmed: 20722779
Am J Reprod Immunol. 2008 Nov;60(5):449-61
pubmed: 19238750
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120

Auteurs

Gayathri Delanerolle (G)

Oxford Brain Health Clinical Trials Unit, University of Oxford, Oxford, UK.
ORCID: 0000-0002-9628-9245

Rema Ramakrishnan (R)

Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK.

Dharani Hapangama (D)

University of Liverpool, Liverpool, UK.
Liverpool Women's NHS Foundation, Liverpool, UK.

Yutian Zeng (Y)

Southern University of Science and Technology, Shenzhen, China.

Ashish Shetty (A)

University College London Hospitals NHS Foundation Trust, London, UK.
University College London, London, UK.

Sohier Elneil (S)

University College London Hospitals NHS Foundation Trust, London, UK.
University College London, London, UK.

Sam Chong (S)

University College London Hospitals NHS Foundation Trust, London, UK.
University College London, London, UK.

Martin Hirsch (M)

University College London Hospitals NHS Foundation Trust, London, UK.
Oxford Health NHS Foundation Trust, Oxford, UK.

Molola Oyewole (M)

University College London Hospitals NHS Foundation Trust, London, UK.
University College London, London, UK.

Peter Phiri (P)

Southern Health NHS Foundation Trust, Southampton, UK.
School of Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, UK.

Kathryn Elliot (K)

Southern Health NHS Foundation Trust, Southampton, UK.

Trusha Kothari (T)

Liverpool Women's NHS Foundation, Liverpool, UK.

Bryony Rogers (B)

University of Liverpool, Liverpool, UK.
Liverpool Women's NHS Foundation, Liverpool, UK.

Natasha Sandle (N)

Oxford Brain Health Clinical Trials Unit, University of Oxford, Oxford, UK.

Nyla Haque (N)

Oxford Brain Health Clinical Trials Unit, University of Oxford, Oxford, UK.

Nicola Pluchino (N)

Divisions of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.

Martin Silem (M)

University Medical Center Freiburg, Freiburg, Germany.

Rebecca O'Hara (R)

Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia.

M Louise Hull (ML)

Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia.

Kingshuk Majumder (K)

Manchester University NHS Foundation Trust, Manchester, UK.

Jian Qing Shi (JQ)

Southern University of Science and Technology, Shenzhen, China.
The Alan Turing Institute, London, UK.

Vanessa Raymont (V)

Oxford Brain Health Clinical Trials Unit, University of Oxford, Oxford, UK.
Department of Psychiatry, University of Oxford, Oxford, UK.

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Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › A systematic review and meta-analysis of the...
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questionsmedicales.fr › Troubles mentaux › Dysfonctionnements sexuels psychogènes › Dyspareunie › A systematic review and meta-analysis of the...
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questionsmedicales.fr › Caractéristiques de la population › Santé › Santé mentale › A systematic review and meta-analysis of the...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Douleur pelvienne › A systematic review and meta-analysis of the...