Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells.


Journal

Evidence-based complementary and alternative medicine : eCAM
ISSN: 1741-427X
Titre abrégé: Evid Based Complement Alternat Med
Pays: United States
ID NLM: 101215021

Informations de publication

Date de publication:
2021
Historique:
received: 12 02 2021
revised: 18 04 2021
accepted: 04 05 2021
entrez: 31 5 2021
pubmed: 1 6 2021
medline: 1 6 2021
Statut: epublish

Résumé

Transplantation of bone marrow mesenchymal stem cells has attracted more and more attention as a regenerative therapy for the treatment of liver diseases. A large number of studies have shown that this kind of cells can inhibit the activation of hepatic stellate cells and regulate tissue homeostasis and immune system via a variety of ways. Meanwhile, bone marrow mesenchymal stem cells can inhibit apoptosis of hepatocyte, improve liver function, and reduce inflammation through multiple pathways. These cells have a broad prospect in the treatment of liver cirrhosis. At present, there are many studies on the specific mechanism of bone marrow mesenchymal stem cells transplantation in the treatment of liver cirrhosis. This paper reviews the pathogenesis of liver cirrhosis and the mechanism of bone marrow mesenchymal stem cells transplantation in the treatment of liver cirrhosis, discusses the effectiveness of traditional Chinese medicine method in enhancing the efficacy of bone marrow mesenchymal stem cells transplantation, and looks forward to its application prospect in the future.

Identifiants

pubmed: 34055009
doi: 10.1155/2021/5569274
pmc: PMC8131131
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

5569274

Informations de copyright

Copyright © 2021 Yaxin Wang et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this paper.

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Auteurs

Yaxin Wang (Y)

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.

Huicun Zhang (H)

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
Beijing Institute of Traditional Chinese Medicine, Beijing 100010, China.

Hongbing Wang (H)

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
Beijing Hospital of Traditional Chinese Medicine Yanqing Hospital, Beijing 102199, China.

Classifications MeSH