Micro-CT and Histomorphometric Study of Bone Regeneration Effect with Autogenous Tooth Biomaterial Enriched with Platelet-Rich Fibrin in an Animal Model.
Journal
Scanning
ISSN: 1932-8745
Titre abrégé: Scanning
Pays: England
ID NLM: 7903371
Informations de publication
Date de publication:
2021
2021
Historique:
received:
02
12
2020
revised:
12
04
2021
accepted:
24
04
2021
entrez:
31
5
2021
pubmed:
1
6
2021
medline:
29
10
2021
Statut:
epublish
Résumé
The aim of this study was to evaluate the potential of tooth biomaterials as bone graft biomaterials for bone healing in rabbits. We prepared tooth biomaterial and platelet-rich fibrin (PRF) to fill the round-shaped defect in the skull of New Zealand white rabbits. These cranial defects were treated with different conditions as follows: group 1, a mixture of tooth biomaterials and platelet-rich fibrin (PRF); group 2, only tooth biomaterials; group 3, only PRF; and group 4, the unfilled control group. Specimens of the filled sites were harvested for analysis with microscopic computerized tomography (micro-CT) and histomorphology at 4 and 8 weeks. As a result of micro-CT, at 4 weeks, the bone volume percentages in groups 1 and 2 were 50.33 ± 6.35 and 57.74 ± 3.13, respectively, and that in the unfilled control group was 42.20 ± 10.53 (
Identifiants
pubmed: 34055131
doi: 10.1155/2021/6656791
pmc: PMC8133871
doi:
Substances chimiques
Biocompatible Materials
0
Fibrin
9001-31-4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
6656791Informations de copyright
Copyright © 2021 Yoon-Ki Lee et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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