Intraoperative Administration of Dexmedetomidine and Dexamethasone in Local Anesthetic Infiltration to Improve Postoperative Pain Control After Posterior Cervical Fusion.
cervical fusion
dex-dex
dexamethasone
dexmedetomidine
multimodal analgesia
pain control
peripheral nerve blocks
postoperative pain
regional anesthesia
spine surgery
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
26 Apr 2021
26 Apr 2021
Historique:
entrez:
31
5
2021
pubmed:
1
6
2021
medline:
1
6
2021
Statut:
epublish
Résumé
Dexmedetomidine, a selective and potent α2-adrenoceptor agonist, is used for its anxiolytic, sedative, and analgesic properties. Dexamethasone is a high-potency, long-acting glucocorticoid that has been shown to provide analgesic and anti-inflammatory effects. At present, little has been published with regard to the effectiveness of these drugs as dual agents with local anesthetics for analgesia. In this report, a case of a 50-year-old man who underwent a cervical spine orthopedic procedure is described, in which an intraoperative injection of ropivacaine was administered with the adjuvants dexmedetomidine and dexamethasone, providing extended postoperative pain relief. In summary, we present a patient who had an injection of ropivacaine with dexmedetomidine and dexamethasone into the erector spinae muscles in the cervical region, which provided improvement in postoperative pain and reduced opioid consumption for five days post-surgery, demonstrating additive and/or synergistic effects beyond the normal local anesthetic duration.
Identifiants
pubmed: 34055542
doi: 10.7759/cureus.14699
pmc: PMC8153515
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e14699Informations de copyright
Copyright © 2021, Southerland et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
J Clin Endocrinol Metab. 1982 May;54(5):1075-7
pubmed: 7061698
Pain Med. 2018 Jul 1;19(7):1485-1493
pubmed: 29036728
Anesth Analg. 2013 Jul;117(1):271-8
pubmed: 23632057
J Clin Anesth. 2020 Aug;63:109750
pubmed: 32109826
Anesthesiology. 1992 Dec;77(6):1125-33
pubmed: 1361310
Int Anesthesiol Clin. 2011 Fall;49(4):104-16
pubmed: 21956081
Anesth Analg. 2019 Mar;128(3):543-554
pubmed: 30303864
Clin Pharmacokinet. 2017 Aug;56(8):893-913
pubmed: 28105598
J Spine Surg. 2019 Sep;5(Suppl 2):S154-S159
pubmed: 31656869
Clin Sci (Lond). 1998 Jun;94(6):557-72
pubmed: 9854452
Reg Anesth Pain Med. 2017 May/Jun;42(3):319-326
pubmed: 28252523
J Clin Anesth. 2020 Jun;62:109705
pubmed: 31935574
J Clin Anesth. 2020 Oct;65:109873
pubmed: 32473512
Acta Anaesthesiol Scand. 1990 Jul;34(5):335-8
pubmed: 2167604
Orthop Clin North Am. 2017 Oct;48(4):445-465
pubmed: 28870305
Anaesthesia. 2015 Jan;70(1):71-83
pubmed: 25123271
Reg Anesth Pain Med. 2019 Aug 8;:
pubmed: 31399540
Best Pract Res Clin Anaesthesiol. 2018 Jun;32(2):83-99
pubmed: 30322466
Br J Anaesth. 2017 Aug 1;119(2):183-191
pubmed: 28854551
Eur J Anaesthesiol. 2010 Mar;27(3):280-4
pubmed: 19935071