Profile and Epidemiology of Intussusception in Children Under-Two Years of Age: A Prospective Surveillance.


Journal

Indian journal of pediatrics
ISSN: 0973-7693
Titre abrégé: Indian J Pediatr
Pays: India
ID NLM: 0417442

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 24 11 2020
accepted: 13 04 2021
pubmed: 1 6 2021
medline: 15 12 2021
entrez: 31 5 2021
Statut: ppublish

Résumé

To report background intussusception epidemiology in children under-two years in Coimbatore district of Tamil Nadu state, India, prior to rotavirus vaccine (RVV) introduction. Prospective sentinel surveillance was done at four hospitals in Coimbatore during April 2016 to September 2017. The children aged >1 mo and < 24 mo with diagnosed intussusception were recruited and data on clinical, treatment, diet, immunization, and sociodemography were collected. Sixty-eight children with intussusception were recruited. Among them 76.5% were infants with male predominance (57.4%) and 48.5% were 4-8 mo old. Vomiting (83.8%), pain in abdomen (including excessive crying) (72.1%), and bloody stools (45.6%) were the main symptoms. Reduction was tried in 92.6% cases with success in 83.8%. Surgery was needed by 16.2% children. No child died. Any RVV dose was received by 24.1% children and 2 children received RVV in 8-21 d and none within 1-7 d window. The incidence of intussusception requiring hospitalization was estimated to be 36.4 and 11.7 cases/100,000 children/y for the first and second years, respectively. Intussusception occurred in infants even without RVV exposure. Continued surveillance is needed to document the changes in intussusception epidemiology after RVV introduction.

Identifiants

pubmed: 34057604
doi: 10.1007/s12098-021-03776-8
pii: 10.1007/s12098-021-03776-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1187-1194

Subventions

Organisme : Bill and Melinda Gates Foundation
ID : OPP1116433

Informations de copyright

© 2021. Dr. K C Chaudhuri Foundation.

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Auteurs

Manoja Kumar Das (MK)

The INCLEN Trust International, F1/5, Okhla Industrial Area, Phase 1, New Delhi, 110020, India. manoj@inclentrust.org.

Narendra Kumar Arora (NK)

The INCLEN Trust International, F1/5, Okhla Industrial Area, Phase 1, New Delhi, 110020, India.

John Mathai (J)

Department of Paediatrics, Masonic Medical Centre for Children, Racecourse, Coimbatore, Tamil Nadu, India.

Cenita J Sam (CJ)

Department of Paediatric Surgery, PSG Institute of Medical Sciences, Peelamedu, Coimbatore, Tamil Nadu, India.

Rajamani G (R)

Department of Paediatric Surgery, Coimbatore Medical College, Trichy Road, Coimbatore, Tamil Nadu, India.

Krishnaswamy R (K)

Department of Pediatrics, Masonic Children's Hospital, Coimbatore, Tamil Nadu, India.

Jothilakshmi K (J)

Department of Paediatrics, PSG Institute of Medical Sciences, Peelamedu, Tamil Nadu, Coimbatore, India.

Pavai Arunachalam (P)

Department of Paediatric Surgery, PSG Institute of Medical Sciences, Peelamedu, Coimbatore, Tamil Nadu, India.

Bini Gupta (B)

The INCLEN Trust International, F1/5, Okhla Industrial Area, Phase 1, New Delhi, 110020, India.

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