In Silico Modeling of the Mitochondrial Pumping Complexes with Markov State Models.
Gillespie algorithm
Markov state models
Mitochondria
Proton pumping
Rate constants
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
1
6
2021
pubmed:
2
6
2021
medline:
9
7
2021
Statut:
ppublish
Résumé
The mechanism of proton pumping by the mitochondrial electron transport chain complexes is still enigmatic after decades of research. Recently, there has been interest in in silico Markov state models to model the mitochondrial pumping complexes at the microscopic level, and this chapter describes the methods of constructing and simulating such models.
Identifiants
pubmed: 34060059
doi: 10.1007/978-1-0716-1266-8_31
doi:
Substances chimiques
Proton Pumps
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
425-439Références
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