Relationship between renal dysfunction and electrolyte abnormalities in hematopoietic stem cell transplant patients treated with foscarnet.


Journal

Journal of chemotherapy (Florence, Italy)
ISSN: 1973-9478
Titre abrégé: J Chemother
Pays: England
ID NLM: 8907348

Informations de publication

Date de publication:
Dec 2021
Historique:
pubmed: 2 6 2021
medline: 4 2 2022
entrez: 1 6 2021
Statut: ppublish

Résumé

This study aimed to investigate the relationship between renal dysfunction and electrolyte abnormalities, which are adverse events of foscarnet used for cytomegalovirus infection. Of the Ninety hematopoietic stem cell transplantation patients, 32 who met the selection criteria were enrolled in this retrospective study. The study patients were divided into two groups according to whether they developed renal dysfunction. The incidences of hypocalcemia, hypokalemia, and hypomagnesemia with an increase of grade 2 or higher in the renal dysfunction group were 45.5%, 18.2%, and 27.3%, respectively. Additionally, in the renal dysfunction group, a significant correlation was observed between creatinine and calcium (r = -0.458,

Identifiants

pubmed: 34060436
doi: 10.1080/1120009X.2021.1915074
doi:

Substances chimiques

Antiviral Agents 0
Electrolytes 0
Foscarnet 364P9RVW4X
Creatinine AYI8EX34EU
Magnesium I38ZP9992A

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

539-546

Auteurs

Ryosuke Ota (R)

Department of Pharmacy, Kindai University Nara Hospital, Ikoma, Japan.

Atsushi Hirata (A)

Department of Pharmacy, Kindai University Nara Hospital, Ikoma, Japan.

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Classifications MeSH