Capillary Electrophoresis Instruments for Medical Applications and Falsified Drug Analysis/Quality Control in Developing Countries.


Journal

Analytical chemistry
ISSN: 1520-6882
Titre abrégé: Anal Chem
Pays: United States
ID NLM: 0370536

Informations de publication

Date de publication:
15 06 2021
Historique:
pubmed: 2 6 2021
medline: 1 7 2021
entrez: 1 6 2021
Statut: ppublish

Résumé

The implementation of integrated analytical techniques to meet stringent requirements in the life sciences requires a well-developed analytical capacity. New technology in analytical equipment for the analysis of large and small molecules is continuously being developed. However, developing countries frequently struggle to keep pace with technological advancements. Hence, it is of utmost importance to better invest in optimizing existing and proven methodologies to tackle life-saving challenges in developing countries. In this regard, capillary electrophoresis is a promising candidate for solving multiple analytical problems compared to its chromatographic and spectroscopic counterparts due to its fast analytical response time and notable cost efficiency. In the following, we summarize various issues and opportunities for capillary electrophoresis to be the technique of choice for the unresolved bottlenecks in analytical equipment in developing countries for drug quality control. This perspective demonstrates that the ongoing quest for the design of new, impactful analytical techniques is a dynamic and rapidly developing research area and mentions some directions and opportunities that have arisen during the recent pandemic.

Identifiants

pubmed: 34061489
doi: 10.1021/acs.analchem.1c00839
doi:

Substances chimiques

Counterfeit Drugs 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8107-8115

Auteurs

Elena Tobolkina (E)

Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CH-1211 Geneva 4, Switzerland.

Serge Rudaz (S)

Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CH-1211 Geneva 4, Switzerland.

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Classifications MeSH