Investigating the Influence of Excipients on the Stability of Levothyroxine Sodium Pentahydrate.

Chemistry, Pharmaceutical Drug Compounding / methods Drug Stability Excipients / chemistry Powders / chemistry Tablets / chemistry Thyroxine / chemistry Water / chemistry Wettability

drug product excipient compatibility levothyroxine salt disproportionation stability

Journal

Molecular pharmaceutics

ISSN: 1543-8392

Titre abrégé: Mol Pharm

Pays: United States

ID NLM: 101197791

Informations de publication

Date de publication:
05 07 2021

Historique:

pubmed: 2 6 2021

medline: 11 1 2022

entrez: 1 6 2021

Statut: ppublish

Résumé

A range of tablet excipients were evaluated for their influence on the physical form and chemical stability of levothyroxine sodium pentahydrate (LSP; C

Identifiants

DOI: 10.1021/acs.molpharmaceut.1c00217 PMID: 34061524

pubmed: 34061524

doi: 10.1021/acs.molpharmaceut.1c00217

doi:

Substances chimiques

Excipients 0

Powders 0

Tablets 0

Water 059QF0KO0R

Thyroxine Q51BO43MG4

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

Pagination

2683-2693

Investigating the Influence of Excipients on the Stability of Levothyroxine Sodium Pentahydrate.

Journal

Informations de publication

Résumé

Identifiants

Substances chimiques

Types de publication

Langues

Sous-ensembles de citation

Pagination

Auteurs

Navpreet Kaur (N)

Raj Suryanarayanan (R)

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Classifications MeSH