High Levels of Low-Density Lipoproteins Correlate with Improved Survival in Patients with Squamous Cell Carcinoma of the Head and Neck.

SCCHN lipoprotein prognosis

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
04 May 2021
Historique:
received: 08 04 2021
revised: 29 04 2021
accepted: 02 05 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 3 6 2021
Statut: epublish

Résumé

Circulating lipoproteins as risk factors or prognostic indicators for various cancers have been investigated previously; however, no clear consensus has been reached. In this study, we aimed at evaluating the impact of serum lipoproteins on the prognosis of patients with squamous cell carcinoma of the head and neck (SCCHN). Levels of total cholesterol, low-density lipoproteins (LDL), high-density lipoproteins (HDL), triglycerides and lipoprotein(a) were measured in serum samples from 106 patients and 28 healthy controls. We found that HDL was the only lipoprotein exhibiting a significant difference in concentration between healthy controls and patients (

Identifiants

pubmed: 34064440
pii: biomedicines9050506
doi: 10.3390/biomedicines9050506
pmc: PMC8147766
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Lion's Cancer Research Foundation, Umeå University
ID : NA
Organisme : The Swedish Cancer Society
ID : 20 0754 PjF 01H
Organisme : Umeå University
ID : NA
Organisme : Region Västerbotten
ID : NA
Organisme : Ministry of Health Czech Republic, conceptual development of research organization
ID : MMCI, 00209805

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Auteurs

Torben Wilms (T)

Department of Medical Biosciences, Umea University, Umea, 901 87 Vasterbotten, Sweden.
Department of Clinical Sciences, Umea University, Umea, 901 87 Vasterbotten, Sweden.

Linda Boldrup (L)

Department of Medical Biosciences, Umea University, Umea, 901 87 Vasterbotten, Sweden.

Xiaolian Gu (X)

Department of Medical Biosciences, Umea University, Umea, 901 87 Vasterbotten, Sweden.

Philip J Coates (PJ)

Research Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, 656 53 Southern Moravia, Czech Republic.

Nicola Sgaramella (N)

Department of Medical Biosciences, Umea University, Umea, 901 87 Vasterbotten, Sweden.

Karin Nylander (K)

Department of Medical Biosciences, Umea University, Umea, 901 87 Vasterbotten, Sweden.

Classifications MeSH