Upper Motor Neuron Disorders: Primary Lateral Sclerosis, Upper Motor Neuron Dominant Amyotrophic Lateral Sclerosis, and Hereditary Spastic Paraplegia.
amyotrophic lateral sclerosis
hereditary spastic paraplegia
primary lateral sclerosis
Journal
Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646
Informations de publication
Date de publication:
11 May 2021
11 May 2021
Historique:
received:
02
04
2021
revised:
02
05
2021
accepted:
10
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
3
6
2021
Statut:
epublish
Résumé
Following the exclusion of potentially reversible causes, the differential for those patients presenting with a predominant upper motor neuron syndrome includes primary lateral sclerosis (PLS), hereditary spastic paraplegia (HSP), or upper motor neuron dominant ALS (UMNdALS). Differentiation of these disorders in the early phases of disease remains challenging. While no single clinical or diagnostic tests is specific, there are several developing biomarkers and neuroimaging technologies which may help distinguish PLS from HSP and UMNdALS. Recent consensus diagnostic criteria and use of evolving technologies will allow more precise delineation of PLS from other upper motor neuron disorders and aid in the targeting of potentially disease-modifying therapeutics.
Identifiants
pubmed: 34064596
pii: brainsci11050611
doi: 10.3390/brainsci11050611
pmc: PMC8151104
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Amyotroph Lateral Scler Frontotemporal Degener. 2017 May;18(3-4):153-174
pubmed: 28054827
Mov Disord. 2007 Oct 31;22(14):2057-62
pubmed: 17702034
Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Dec;1(5):293-9
pubmed: 11464847
Can J Neurol Sci. 1977 Nov;4(4):251-8
pubmed: 597798
Muscle Nerve. 2007 Mar;35(3):291-302
pubmed: 17212349
J Neurol Neurosurg Psychiatry. 2016 Jan;87(1):12-20
pubmed: 26296871
Pract Neurol. 2020 Aug;20(4):262-269
pubmed: 32217663
J Neurol Neurosurg Psychiatry. 2004 Dec;75(12):1768-71
pubmed: 15548503
Arch Neurol. 1981 Oct;38(10):630-3
pubmed: 7295106
Neurology. 2012 Aug 28;79(9):878-82
pubmed: 22843265
Neurology. 2021 Apr 27;96(17):e2231-e2238
pubmed: 33637635
Mol Neurodegener. 2020 Oct 15;15(1):58
pubmed: 33059698
Mayo Clin Proc. 2018 Nov;93(11):1617-1628
pubmed: 30401437
Neurology. 2007 Apr 3;68(14):1156-7
pubmed: 17404201
Cerebellum. 2017 Apr;16(2):525-551
pubmed: 27271711
JAMA Neurol. 2017 May 1;74(5):525-532
pubmed: 28264096
Brain. 1992 Apr;115 ( Pt 2):495-520
pubmed: 1606479
J Neurol Sci. 2020 Oct 15;417:117052
pubmed: 32731060
Acta Neuropathol. 2009 Apr;117(4):429-44
pubmed: 19194716
Ann Neurol. 2018 Feb;83(2):258-268
pubmed: 29331073
Amyotroph Lateral Scler Frontotemporal Degener. 2020 Nov;21(sup1):52-58
pubmed: 32657153
J Neurol Neurosurg Psychiatry. 2019 Feb;90(2):141-147
pubmed: 30076267
J Clin Neuromuscul Dis. 2016 Mar;17(3):99-105
pubmed: 26905909
Neurology. 2007 Apr 24;68(17):1402-10
pubmed: 17452585
J Neurol. 2019 May;266(5):1079-1090
pubmed: 30834979
AJNR Am J Neuroradiol. 2007 Feb;28(2):250-4
pubmed: 17296988
Arch Neurol. 2007 Feb;64(2):232-6
pubmed: 17296839
J Neurol. 2007 Aug;254(8):1033-6
pubmed: 17294065
Exp Neurol. 2014 Nov;261:518-39
pubmed: 24954637
J Neurol Neurosurg Psychiatry. 2020 Apr;91(4):373-377
pubmed: 32029539
J Neurol. 2019 Nov;266(11):2718-2733
pubmed: 31325016
Muscle Nerve. 2020 Feb;61(2):163-172
pubmed: 31758557
Amyotroph Lateral Scler. 2009 Oct-Dec;10(5-6):339-46
pubmed: 19922121
J Neurol Neurosurg Psychiatry. 2019 Nov;90(11):1215-1220
pubmed: 31123140
Neurodegener Dis. 2018;18(5-6):255-261
pubmed: 30428468
Neurology. 2006 Mar 14;66(5):647-53
pubmed: 16534101
J Neurol Neurosurg Psychiatry. 2012 Apr;83(4):399-403
pubmed: 22100761
Lancet Neurol. 2015 May;14(5):478-84
pubmed: 25843898
Brain. 2006 Jul;129(Pt 7):1710-9
pubmed: 16670179
Acta Neuropathol. 1977 Jun 15;38(3):225-8
pubmed: 197771
Clin Neuropathol. 2004 Jul-Aug;23(4):183-93
pubmed: 15328884
Noro Psikiyatr Ars. 2019 Aug 16;57(3):228-233
pubmed: 32952426
J Neurol Neurosurg Psychiatry. 1995 Jun;58(6):742-4
pubmed: 7608680
Acta Neuropathol. 2007 Jul;114(1):71-9
pubmed: 17569066
Acta Neuropathol. 1988;76(2):208-11
pubmed: 3407398
J Neurol Neurosurg Psychiatry. 1994 Oct;57(10):1280-1
pubmed: 7931406
Ann Clin Transl Neurol. 2018 May 21;5(7):876-882
pubmed: 30009206
Arch Neurol. 1988 Dec;45(12):1304-7
pubmed: 3196189
Neuropathol Appl Neurobiol. 2019 Apr;45(3):291-304
pubmed: 29908069
J Neurol. 2020 Jun;267(6):1699-1708
pubmed: 32100123
J Neurol. 2018 Aug;265(8):1819-1828
pubmed: 29868980
Amyotroph Lateral Scler Frontotemporal Degener. 2018 May;19(3-4):232-241
pubmed: 29214883
Neurology. 2003 Apr 22;60(8):1258-65
pubmed: 12707427
Arch Neurol. 2009 Apr;66(4):509-14
pubmed: 19364936
Br Med J. 1902 Oct 11;2(2180):1114-9
pubmed: 20760476
Eur J Neurol. 2015 May;22(5):826-31, e57-8
pubmed: 25683471
Neuroimage Clin. 2012 Dec 24;2:151-60
pubmed: 24179768
Amyotroph Lateral Scler Frontotemporal Degener. 2014 Jun;15(3-4):192-203
pubmed: 24564738
Amyotroph Lateral Scler Frontotemporal Degener. 2019 Aug;20(5-6):376-384
pubmed: 31134825
Semin Neurol. 2001 Jun;21(2):199-207
pubmed: 11442328
Zh Nevropatol Psikhiatr Im S S Korsakova. 1962;62:1293-9
pubmed: 14016841
Suppl Clin Neurophysiol. 2009;60:153-62
pubmed: 20715377
Data Brief. 2020 Sep 01;32:106246
pubmed: 32944601
Neuroimage Clin. 2017 Dec 18;17:953-961
pubmed: 29321969
J Neurol Neurosurg Psychiatry. 2001 Nov;71(5):615-20
pubmed: 11606672
Acta Neuropathol. 2003 Jun;105(6):615-20
pubmed: 12734667
Amyotroph Lateral Scler Other Motor Neuron Disord. 2002 Dec;3(4):190-8
pubmed: 12710508
Neurol Genet. 2015 Apr 14;1(1):e3
pubmed: 27066542
Muscle Nerve. 2013 Jan;47(1):28-32
pubmed: 23169452
Rev Neurol (Paris). 2015 Jun-Jul;171(6-7):505-30
pubmed: 26008818
Acta Neuropathol. 2013 Sep;126(3):307-28
pubmed: 23897027
Brain. 2014 Sep;137(Pt 9):2546-55
pubmed: 24951638
Acta Neuropathol. 2013 Oct;126(4):537-544
pubmed: 23995422
J Neurol Sci. 2012 Dec 15;323(1-2):147-53
pubmed: 23026537
Front Neurosci. 2019 Jul 12;13:704
pubmed: 31354413
Hum Brain Mapp. 2014 Apr;35(4):1710-22
pubmed: 23633431
J Clin Neuromuscul Dis. 2005 Sep;7(1):1-9
pubmed: 19078775
J Neurol. 1995 Jan;242(2):59-63
pubmed: 7707090
Neurosci Lett. 1988 Nov 22;94(1-2):203-10
pubmed: 2853853
Neurol Clin. 2015 Nov;33(4):749-60
pubmed: 26515619
J Neurol Neurosurg Psychiatry. 1974 Jan;37(1):8-20
pubmed: 4813430
Arch Neurol. 2010 Jan;67(1):122-5
pubmed: 20065142
Neurology. 2009 Jun 2;72(22):1948-52
pubmed: 19487653
Brain. 2001 Oct;124(Pt 10):1989-99
pubmed: 11571217
J Neurol Sci. 2010 Nov 15;298(1-2):70-7
pubmed: 20810131
J Neurol. 2020 Aug;267(8):2272-2280
pubmed: 32306171
Neurosci Lett. 1988 Nov 11;93(2-3):197-203
pubmed: 2853844