Contrast Associated Acute Kidney Injury and Mortality in Older Adults with Acute Coronary Syndrome: A Pooled Analysis of the FRASER and HULK Studies.
acute coronary syndrome
contrast induced acute kidney injury
mortality
older patients
percutaneous coronary intervention
physical performance
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
16 May 2021
16 May 2021
Historique:
received:
29
03
2021
revised:
26
04
2021
accepted:
27
04
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
3
6
2021
Statut:
epublish
Résumé
Whether contrast-associated acute kidney injury (CA-AKI) is only a bystander or a risk factor for mortality in older patients undergoing percutaneous coronary intervention (PCI) is not well understood. Data from FRASER (NCT02386124) and HULK (NCT03021044) studies have been analysed. All patients enrolled underwent coronary angiography. The occurrence of CA-AKI was defined based on KDIGO criteria. The primary outcome of the study was to test the relation between CA-AKI and 3-month mortality. Overall, 870 older ACS adults were included in the analysis (mean age 78 ± 5 years; 28% females). CA-AKI occurred in 136 (16%) patients. At 3 months, 13 (9.6%) patients with CA-AKI died as compared with 13 (1.8%) without it (
Identifiants
pubmed: 34065642
pii: jcm10102151
doi: 10.3390/jcm10102151
pmc: PMC8156026
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Italian Health Ministry Ricerca Finalizzata 2018
ID : GR-2018-12367114
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