SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction.

COVID-19 SARS-CoV-2 arteritis pathology testicular infarction

Journal

Clinics and practice
ISSN: 2039-7275
Titre abrégé: Clin Pract
Pays: Switzerland
ID NLM: 101563282

Informations de publication

Date de publication:
06 May 2021
Historique:
received: 19 03 2021
revised: 12 04 2021
accepted: 21 04 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 3 6 2021
Statut: epublish

Résumé

A 26-year-old man with symptomatic SARS-CoV-2 infection developed a sudden-onset acute testicular pain. The echo-doppler images showed massive testicular infarction, so orchiectomy was performed. On gross examination, the surgical specimen showed complete testicular necrosis and diffuse thickening of the testicular coverings. Under the microscope, a severe obliterative arteritis was evidenced. SARS-CoV-2 spike antibody was detected by immunohistochemistry in the arterial endothelium. Electron microscopy displayed intracytoplasmic spiky viral particles in endothelial cells. The patient was treated with corticoids and was asymptomatic at last contact.

Identifiants

pubmed: 34066311
pii: clinpract11020037
doi: 10.3390/clinpract11020037
pmc: PMC8161438
doi:

Types de publication

Case Reports

Langues

eng

Pagination

246-249

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Auteurs

Dámaso Parrón (D)

Department of Pathology, Cruces University Hospital, Barakaldo, 48903 Bizkaia, Spain.

Ane Gartzia (A)

Department of Pathology, Cruces University Hospital, Barakaldo, 48903 Bizkaia, Spain.

Ane M Iturregui (AM)

Department of Urology, Cruces University Hospital, Barakaldo, 48903 Bizkaia, Spain.

Igone Imaz (I)

Department of Pathology, Cruces University Hospital, Barakaldo, 48903 Bizkaia, Spain.

Claudia Manini (C)

Department of Pathology, San Giovanni Bosco Hospital, 10154 Turin, Italy.

Jorge García-Olaverri (J)

Department of Urology, Cruces University Hospital, Barakaldo, 48903 Bizkaia, Spain.

José I López (JI)

Department of Pathology, Cruces University Hospital, Barakaldo, 48903 Bizkaia, Spain.
Biocruces-Bizkaia Health Research Institute, Barakaldo, 48903 Bizkaia, Spain.

Classifications MeSH