Retriever and Pointer: Software to Evaluate Inbreeding and Genetic Management in Captive Populations.

animal breeding conservation genetic management genetic resources inbreeding software

Journal

Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614

Informations de publication

Date de publication:
07 May 2021
Historique:
received: 18 03 2021
revised: 23 04 2021
accepted: 28 04 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 3 6 2021
Statut: epublish

Résumé

The Retriever and Pointer software has been developed for genetic management of (small) captive populations The Retriever program uses as input pedigree data and extracts data on population structure that determine inbreeding rates such as skewness of sire contributions. Levels and rates of inbreeding and kinship and effective population sizes are determined as well. Data on population structure can be used as input for the Pointer program. This program uses stochastic simulation to evaluate a population and provides expected levels and rates of inbreeding and kinship, and optionally allelic diversity. The user can simulate different options for genetic management such as sire restrictions, restrictions on inbreeding levels, mean kinships and breeding circles. Both Retriever and Pointer can analyze populations with subpopulations and different rates of exchange between them. Although originally devised for dogs, the software can be, and has been, used for any captive population including livestock and zoo populations, and a number of examples are provide The pointer software is also suitable in education where students may generate their own populations and evaluate effects of different population structures and genetic management on genetic diversity. Input is provided via a graphical user interface. The software can be downloaded for free.

Identifiants

pubmed: 34067200
pii: ani11051332
doi: 10.3390/ani11051332
pmc: PMC8151292
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Ministerie van Landbouw, Natuur en Voedselkwaliteit
ID : WOT 03-003-056
Organisme : Ministerie van Landbouw, Natuur en Voedselkwaliteit
ID : KB-34-013-002

Références

J Anim Breed Genet. 2019 Jan;136(1):51-62
pubmed: 30548349
Mol Biol Evol. 2019 Mar 1;36(3):632-637
pubmed: 30517680
Vet J. 2019 Jun;248:18-24
pubmed: 31113557
Genet Sel Evol. 2013 Jan 02;45:1
pubmed: 23281913
Animal. 2008 Dec;2(12):1733-41
pubmed: 22444078
J Anim Breed Genet. 2005 Jun;122(3):172-6
pubmed: 16130468
J Anim Breed Genet. 2015 Dec;132(6):428-40
pubmed: 25912813
Genet Sel Evol. 1985;17(4):459-80
pubmed: 22879220
G3 (Bethesda). 2020 Jun 1;10(6):1915-1918
pubmed: 32229505
Bioinformatics. 2009 Mar 1;25(5):680-1
pubmed: 19176551
J Anim Breed Genet. 2020 Jul;137(4):345-355
pubmed: 31713272
J Anim Breed Genet. 2009 Aug;126(4):327-32
pubmed: 19630884
J Anim Breed Genet. 2018 Jun;135(3):238-248
pubmed: 29878495
Genet Mol Res. 2009 Sep 29;8(3):1158-78
pubmed: 19866435
J Anim Breed Genet. 2005 Oct;122(5):325-31
pubmed: 16191041
Prev Vet Med. 2007 Feb 16;78(2):161-71
pubmed: 17095110
J Anim Breed Genet. 2008 Oct;125(5):301-10
pubmed: 18803785

Auteurs

Jack J Windig (JJ)

Wageningen Livestock Research, Animal Breeding and Genomics, Wageningen University & Research, P.O. Box 338, 6700 AH Wageningen, The Netherlands.
Centre for Genetic Resources The Netherlands, Wageningen University & Research, P.O. Box 16, 6700 AA Wageningen, The Netherlands.

Ina Hulsegge (I)

Wageningen Livestock Research, Animal Breeding and Genomics, Wageningen University & Research, P.O. Box 338, 6700 AH Wageningen, The Netherlands.
Centre for Genetic Resources The Netherlands, Wageningen University & Research, P.O. Box 16, 6700 AA Wageningen, The Netherlands.

Classifications MeSH