Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
breast cancer
estrogen
gene-environment interaction
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
14 May 2021
14 May 2021
Historique:
received:
09
04
2021
revised:
29
04
2021
accepted:
30
04
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
3
6
2021
Statut:
epublish
Résumé
In this study we aim to examine gene-environment interactions (GxEs) between genes involved with estrogen metabolism and environmental factors related to estrogen exposure. GxE analyses were conducted with 1970 Korean breast cancer cases and 2052 controls in the case-control study, the Seoul Breast Cancer Study (SEBCS). A total of 11,555 SNPs from the 137 candidate genes were included in the GxE analyses with eight established environmental factors. A replication test was conducted by using an independent population from the Breast Cancer Association Consortium (BCAC), with 62,485 Europeans and 9047 Asians. The GxE tests were performed by using two-step methods in GxEScan software. Two interactions were found in the SEBCS. The first interaction was shown between rs13035764 of NCOA1 and age at menarche in the GE|2df model (
Identifiants
pubmed: 34069208
pii: cancers13102370
doi: 10.3390/cancers13102370
pmc: PMC8156547
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Wellcome Trust
ID : 203477/Z/16/Z
Pays : United Kingdom
Organisme : Seoul National University Hospital
ID : 2021
Organisme : Seoul National University Hospital
ID : 0320150110 (2015-1126)
Références
Breast Cancer Res. 2014 May 26;16(3):R51
pubmed: 24887515
Pediatr Endocrinol Rev. 2007 Jun;4(4):329-34
pubmed: 17643080
Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):342-7
pubmed: 16492926
Breast Cancer Res. 2012 Mar 27;14(2):R56
pubmed: 22452962
Nat Rev Genet. 2010 Apr;11(4):259-72
pubmed: 20212493
Perspect Psychol Sci. 2015 Jan;10(1):37-59
pubmed: 25620996
Breast Cancer Res Treat. 2010 Jun;121(2):281-92
pubmed: 20437200
J Clin Endocrinol Metab. 2003 Feb;88(2):871-8
pubmed: 12574227
Nat Rev Clin Oncol. 2015 Oct;12(10):573-83
pubmed: 26122181
Breast Cancer Res. 2003;5(5):239-47
pubmed: 12927032
Breast Cancer Res Treat. 2011 Apr;126(3):717-27
pubmed: 20872241
Hum Mol Genet. 2016 Aug 1;25(15):3361-3371
pubmed: 27354352
Breast Cancer Res. 2011 Apr 01;13(2):R37
pubmed: 21457551
J Child Psychol Psychiatry. 2017 Mar;58(3):328-330
pubmed: 28194762
J Clin Pathol. 2004 Oct;57(10):1069-74
pubmed: 15452162
Int J Cancer. 2015 Mar 15;136(6):E685-96
pubmed: 25227710
Eur J Pediatr. 2010 Jan;169(1):89-94
pubmed: 19504269
Horm Metab Res. 1994 Oct;26(10):486-8
pubmed: 7851874
JAMA Oncol. 2016 Oct 1;2(10):1295-1302
pubmed: 27228256
Int J Cancer. 2015 Mar 1;136(5):E359-86
pubmed: 25220842
Mol Oncol. 2010 Jun;4(3):174-91
pubmed: 20542480
Int J Epidemiol. 2020 Feb 1;49(1):216-232
pubmed: 31605532
Nat Genet. 2013 Apr;45(4):353-61, 361e1-2
pubmed: 23535729
Am J Epidemiol. 2014 Nov 15;180(10):1018-27
pubmed: 25255808
Int J Cancer. 2017 Nov 1;141(9):1830-1840
pubmed: 28670784
Cancer Epidemiol Biomarkers Prev. 2016 May;25(5):780-90
pubmed: 26976855
J Biomed Biotechnol. 2011;2011:571784
pubmed: 21716904
Breast Cancer Res. 2010;12(6):R110
pubmed: 21194473
J Natl Cancer Inst. 2011 Aug 17;103(16):1252-63
pubmed: 21791674
Nat Genet. 2014 Aug;46(8):886-90
pubmed: 25038754
J Clin Endocrinol Metab. 2004 Jan;89(1):375-83
pubmed: 14715875
Clin Obstet Gynecol. 2016 Dec;59(4):651-672
pubmed: 27681694
Genet Epidemiol. 2013 Sep;37(6):603-13
pubmed: 23873611
Horm Res Paediatr. 2011;75(6):383-91
pubmed: 21540578
Genet Epidemiol. 2014 Jan;38(1):84-93
pubmed: 24248812
Nat Genet. 2015 Apr;47(4):373-80
pubmed: 25751625
Gynecol Endocrinol. 2016 Jul;32(7):553-6
pubmed: 26850117
Clin Exp Med. 2008 Jun;8(2):65-71
pubmed: 18618215
Breast Cancer Res Treat. 2003 Jan;77(1):27-36
pubmed: 12602902
Nat Genet. 2013 Dec;45(12):1446-51
pubmed: 24185510
Breast. 2013 Jun;22(3):335-43
pubmed: 23000097
Hum Mol Genet. 2014 Oct 1;23(19):5260-70
pubmed: 24895409
J Clin Endocrinol Metab. 1999 Dec;84(12):4677-94
pubmed: 10599737
Nat Rev Cancer. 2009 Sep;9(9):615-30
pubmed: 19701241
Lancet. 2019 Aug 31;394(10200):736
pubmed: 31478500
PLoS One. 2008 Mar 19;3(3):e1807
pubmed: 18350145
Cancer Causes Control. 2012 May;23(5):671-81
pubmed: 22418777
CA Cancer J Clin. 2021 May;71(3):209-249
pubmed: 33538338
Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9362-7
pubmed: 19474294
Int J Epidemiol. 2015 Aug;44(4):1130-2
pubmed: 25855723
Cancer Res. 2011 Jun 1;71(11):3881-8
pubmed: 21610108
J Child Psychol Psychiatry. 2017 Mar;58(3):331-334
pubmed: 28194764
Genet Epidemiol. 2013 Nov;37(7):643-57
pubmed: 24123198
Biomedicines. 2017 Aug 14;5(3):
pubmed: 28805722
Epidemiol Rev. 2001;23(2):313-42
pubmed: 12192740
Breast Cancer Res. 2014 Dec 12;16(6):494
pubmed: 25928204
Am J Phys Anthropol. 2008 Jun;136(2):230-6
pubmed: 18324642
Cancer. 2011 Dec 1;117(23):5271-81
pubmed: 21598244
Mol Hum Reprod. 2002 Jul;8(7):644-50
pubmed: 12087079
J Breast Cancer. 2020 Apr 07;23(2):115-128
pubmed: 32395372
Breast Cancer Res Treat. 2003 Mar;78(2):223-76
pubmed: 12725422
Nat Rev Genet. 2005 Apr;6(4):287-98
pubmed: 15803198
Korean J Pediatr. 2011 Nov;54(11):436-42
pubmed: 22253640
Hum Mol Genet. 2009 Mar 15;18(6):1131-9
pubmed: 19126777
Int J Endocrinol. 2015;2015:165215
pubmed: 25873947
J Natl Cancer Inst. 2012 May 2;104(9):657-69
pubmed: 22472546
Genet Epidemiol. 2012 Apr;36(3):183-94
pubmed: 22714933
Breast Cancer Res Treat. 2010 May;121(1):177-84
pubmed: 19760036
Pediatr Endocrinol Rev. 2008 Sep;6(1):32-41
pubmed: 18806723
Breast Cancer Res Treat. 2013 Apr;138(2):529-542
pubmed: 23423446
BMC Cancer. 2009 Apr 20;9:115
pubmed: 19379515
N Engl J Med. 2004 Oct 14;351(16):1619-26
pubmed: 15483280
Nat Genet. 2009 Mar;41(3):324-8
pubmed: 19219042
Eur J Cancer Prev. 2001 Feb;10(1):15-32
pubmed: 11263588
Bioinformatics. 2010 Sep 1;26(17):2190-1
pubmed: 20616382
Biomed Pharmacother. 2016 Mar;78:234-238
pubmed: 26898447
PLoS Genet. 2013;9(3):e1003284
pubmed: 23544014
Nat Genet. 2008 Jan;40(1):17-22
pubmed: 18163131
Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1461-7
pubmed: 19383894
Lancet Oncol. 2001 Mar;2(3):133-40
pubmed: 11902563
J Clin Endocrinol Metab. 2004 Jan;89(1):303-9
pubmed: 14715865
Oncol Rep. 2011 Aug;26(2):479-85
pubmed: 21567099
Reprod Health. 2016 Sep 23;13(1):121
pubmed: 27662834
Breast Care (Basel). 2009;4(2):82-87
pubmed: 20847884
Genome Res. 2005 Nov;15(11):1519-34
pubmed: 16251462
Lancet. 2010 Jun 19;375(9732):2143-51
pubmed: 20605201
Breast Cancer Res Treat. 2013 Aug;140(3):557-65
pubmed: 23901017
Am J Epidemiol. 2007 Feb 1;165(3):262-70
pubmed: 17090617
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2147-53
pubmed: 16172224
Endocr Relat Cancer. 2013 Nov 04;20(6):875-87
pubmed: 24080446
Br J Cancer. 2016 Jan 19;114(2):125-33
pubmed: 26757262
Int J Biol Sci. 2012;8(4):470-85
pubmed: 22419892
J Gynecol Oncol. 2011 Jun 30;22(2):110-9
pubmed: 21860737
Clin Endocrinol (Oxf). 2002 Mar;56(3):291-3
pubmed: 11940038
J Natl Cancer Inst. 2015 Aug 20;107(11):
pubmed: 26296642