Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance.

RNA dependent RNA polymerase SARS-CoV-2 diagnostics evolution genome analysis remdesivir resistance surveillance

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
19 May 2021
Historique:
received: 14 04 2021
revised: 09 05 2021
accepted: 15 05 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 3 6 2021
Statut: epublish

Résumé

A variety of antiviral treatments for COVID-19 have been investigated, involving many repurposed drugs. Currently, the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp, encoded by

Identifiants

pubmed: 34069681
pii: microorganisms9051094
doi: 10.3390/microorganisms9051094
pmc: PMC8160703
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Alfredo Mari (A)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.
Division of Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.

Tim Roloff (T)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.
Division of Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.

Madlen Stange (M)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.
Division of Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.

Kirstine K Søgaard (KK)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.
Division of Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.

Erblin Asllanaj (E)

SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.
Biozentrum, University of Basel, Klingelbergstrasse 50-70, CH-4056 Basel, Switzerland.

Gerardo Tauriello (G)

SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.
Biozentrum, University of Basel, Klingelbergstrasse 50-70, CH-4056 Basel, Switzerland.

Leila Tamara Alexander (LT)

SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.
Biozentrum, University of Basel, Klingelbergstrasse 50-70, CH-4056 Basel, Switzerland.

Michael Schweitzer (M)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.
Division of Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.

Karoline Leuzinger (K)

Clinical Virology, University Hospital Basel, 4031 Basel, Switzerland.
Transplantation & Clinical Virology, Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.

Alexander Gensch (A)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.

Aurélien E Martinez (AE)

Infectious Diseases and Hospital Epidemiology, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.

Julia Bielicki (J)

Pediatric Infectious Diseases, University of Basel Children's Hospital, 4056 Basel, Switzerland.

Hans Pargger (H)

Intensive Care Medicine, University Hospital Basel, 4031 Basel, Switzerland.

Martin Siegemund (M)

Intensive Care Medicine, University Hospital Basel, 4031 Basel, Switzerland.

Christian H Nickel (CH)

Emergency Medicine, University Hospital Basel, 4031 Basel, Switzerland.

Roland Bingisser (R)

Emergency Medicine, University Hospital Basel, 4031 Basel, Switzerland.

Michael Osthoff (M)

Internal Medicine, University Hospital Basel, 4031 Basel, Switzerland.

Stefano Bassetti (S)

Internal Medicine, University Hospital Basel, 4031 Basel, Switzerland.

Parham Sendi (P)

Infectious Diseases and Hospital Epidemiology, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
Institute for Infectious Diseases, University of Bern, 3001 Bern, Switzerland.

Manuel Battegay (M)

Infectious Diseases and Hospital Epidemiology, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.

Catia Marzolini (C)

Infectious Diseases and Hospital Epidemiology, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.

Helena M B Seth-Smith (HMB)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.
Division of Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.

Torsten Schwede (T)

SIB Swiss Institute of Bioinformatics, 4053-4056 Basel, Switzerland.
Biozentrum, University of Basel, Klingelbergstrasse 50-70, CH-4056 Basel, Switzerland.

Hans H Hirsch (HH)

Clinical Virology, University Hospital Basel, 4031 Basel, Switzerland.
Transplantation & Clinical Virology, Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.
Infectious Diseases and Hospital Epidemiology, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.

Adrian Egli (A)

Applied Microbiology Research, Department of Biomedicine, University of Basel, 4056 Basel, Switzerland.
Division of Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.

Classifications MeSH