Comparison of Acute Kidney Injury in Patients with COVID-19 and Other Respiratory Infections: A Prospective Cohort Study.

COVID-19 SARS-CoV-2 acute kidney injury mortality pneumonia respiratory tract infection

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
25 May 2021
Historique:
received: 22 04 2021
revised: 10 05 2021
accepted: 22 05 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 3 6 2021
Statut: epublish

Résumé

Previous studies have indicated an association between coronavirus disease 2019 (COVID-19) and acute kidney injury (AKI) but lacked a control group. The prospective observational COronaVIrus-surviVAl (COVIVA) study performed at the University Hospital, Basel, Switzerland consecutively enrolled patients with symptoms suggestive of COVID-19. We compared patients who tested positive for SARS-CoV-2 with patients who tested negative but with an adjudicated diagnosis of a respiratory tract infection, including pneumonia. The primary outcome measure was death at 30 days, and the secondary outcomes were AKI incidence and a composite endpoint of death, intensive care treatment or rehospitalization at 30 days. Five hundred and seven patients were diagnosed with respiratory tract infections, and of those, 183 (36%) had a positive PCR swab test for SARS-CoV-2. The incidence of AKI was higher in patients with COVID-19 (30% versus 12%,

Identifiants

pubmed: 34070339
pii: jcm10112288
doi: 10.3390/jcm10112288
pmc: PMC8197451
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Schweizerische Herzstiftung
ID : na
Organisme : Cardiovascular Research Foundation Basel
ID : na
Organisme : Roche Diagnostics
ID : na

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Auteurs

Matthias Diebold (M)

Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Tobias Zimmermann (T)

Department of Intensive Care Medicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Michael Dickenmann (M)

Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Stefan Schaub (S)

Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Stefano Bassetti (S)

Division of Internal Medicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Sarah Tschudin-Sutter (S)

Department of Clinical Research, University of Basel, 4031 Basel, Switzerland.
Division of Infectious Disease & Hospital Epidemiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Roland Bingisser (R)

Emergency Department, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Corin Heim (C)

Emergency Department, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Martin Siegemund (M)

Department of Intensive Care Medicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.
Department of Clinical Research, University of Basel, 4031 Basel, Switzerland.

Stefan Osswald (S)

Department of Cardiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Gabriela M Kuster (GM)

Department of Cardiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Katharina M Rentsch (KM)

Department of Laboratory Medicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Tobias Breidthardt (T)

Division of Internal Medicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.

Raphael Twerenbold (R)

Department of Cardiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.
Department of Cardiology and University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, 20246 Hamburg, Germany.

Classifications MeSH