Oncological Frontiers in the Treatment of Malignant Pleural Mesothelioma.
immunotherapy
malignant pleural mesothelioma
target therapy
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
25 May 2021
25 May 2021
Historique:
received:
20
04
2021
revised:
09
05
2021
accepted:
18
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
3
6
2021
Statut:
epublish
Résumé
Malignant pleural mesothelioma (MPM) is a rare malignancy characterized by very poor prognosis and lack of treatment options. Immunotherapy has rapidly emerged as an effective tool for MPM, particularly for tumors of non-epithelioid histology. At the same time, comprehensive genomic sequencing may open the way to new-generation targeted-drugs able to hit specific MPM molecular vulnerabilities. These innovations will possibly enrich, but also dramatically complicate, the elucidation of treatment algorithms. Multidisciplinary integration is urgently needed.
Identifiants
pubmed: 34070352
pii: jcm10112290
doi: 10.3390/jcm10112290
pmc: PMC8197557
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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