Effect of Vitamin D Supplementation on Skeletal Muscle Volume and Strength in Patients with Decompensated Liver Cirrhosis Undergoing Branched Chain Amino Acids Supplementation: A Prospective, Randomized, Controlled Pilot Trial.
decompensated liver cirrhosis
sarcopenia
skeletal muscle mass index
vitamin D
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
30 May 2021
30 May 2021
Historique:
received:
29
04
2021
revised:
25
05
2021
accepted:
27
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
29
7
2021
Statut:
epublish
Résumé
Sarcopenia worsens patient prognoses in chronic liver disease. This study aimed to elucidate the effects of vitamin D supplementation on skeletal muscle volume and strength in patients with decompensated cirrhosis. Thirty-three patients were entered into the study based on the criteria and then randomly assigned to two groups: Group A ( SMI values in Group B were significantly increased at 12 months (7.64 × 10 Vitamin D supplementation might be an effective and safe treatment option for patients with decompensated cirrhosis to increase or restore the skeletal muscle volume and strength or prevent the muscle volume and strength losses.
Sections du résumé
BACKGROUND
BACKGROUND
Sarcopenia worsens patient prognoses in chronic liver disease. This study aimed to elucidate the effects of vitamin D supplementation on skeletal muscle volume and strength in patients with decompensated cirrhosis.
METHODS
METHODS
Thirty-three patients were entered into the study based on the criteria and then randomly assigned to two groups: Group A (
RESULTS
RESULTS
SMI values in Group B were significantly increased at 12 months (7.64 × 10
CONCLUSIONS
CONCLUSIONS
Vitamin D supplementation might be an effective and safe treatment option for patients with decompensated cirrhosis to increase or restore the skeletal muscle volume and strength or prevent the muscle volume and strength losses.
Identifiants
pubmed: 34070910
pii: nu13061874
doi: 10.3390/nu13061874
pmc: PMC8228227
pii:
doi:
Substances chimiques
Amino Acids, Branched-Chain
0
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
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