Clinical and Neurophysiological Effects of Botulinum Neurotoxin Type A in Chronic Migraine.


Journal

Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765

Informations de publication

Date de publication:
29 05 2021
Historique:
received: 30 04 2021
revised: 20 05 2021
accepted: 24 05 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 6 7 2021
Statut: epublish

Résumé

Chronic pain syndromes present a subversion of both functional and structural nociceptive networks. We used transcranial magnetic stimulation (TMS) to evaluate changes in cortical excitability and plasticity in patients with chronic migraine (CM) treated with botulinum neurotoxin type A (BoNT/A). We enrolled 11 patients with episodic migraine (EM) and 11 affected by CM. Baseline characteristics for both groups were recorded using single- and paired-pulse TMS protocols. The same TMS protocol was repeated in CM patients after four cycles of BoNT/A completed in one year. At baseline, compared with EM patients, patients with CM had a lower threshold in both hemispheres (right hemisphere: 46% ± 7.8 vs. 52% ± 4.28,

Identifiants

pubmed: 34072379
pii: toxins13060392
doi: 10.3390/toxins13060392
pmc: PMC8229748
pii:
doi:

Substances chimiques

Botulinum Toxins, Type A EC 3.4.24.69

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

Cephalalgia. 2010 Jul;30(7):804-14
pubmed: 20647171
PLoS Pathog. 2012 Dec;8(12):e1003087
pubmed: 23300443
Cochrane Database Syst Rev. 2018 Jun 25;6:CD011616
pubmed: 29939406
Ann Neurol. 1996 Sep;40(3):367-78
pubmed: 8797526
Neurology. 2009 Feb 3;72(5 Suppl):S3-7
pubmed: 19188564
Electroencephalogr Clin Neurophysiol. 1994 Aug;91(2):79-92
pubmed: 7519144
Biol Psychiatry. 2009 Jul 1;66(1):54-61
pubmed: 19368897
Toxicon. 2020 May;179:1-7
pubmed: 32174507
Neural Plast. 2015;2015:205985
pubmed: 26366304
Pain. 2011 Mar;152(3 Suppl):S49-S64
pubmed: 21146929
Neurology. 1998 Apr;50(4):1111-4
pubmed: 9566403
J Neurol. 2013 Aug;260(8):1960-9
pubmed: 23132299
Cephalalgia. 2018 Jan;38(1):1-211
pubmed: 29368949
Neuron. 2016 Jan 6;89(1):11-36
pubmed: 26748087
Headache. 2010 Oct;50(9):1406-18
pubmed: 20958294
Brain. 2016 Jul;139(Pt 7):2002-14
pubmed: 27246325
Clin Neurophysiol. 2015 Jun;126(6):1071-1107
pubmed: 25797650
Neurotoxicology. 2005 Oct;26(5):785-93
pubmed: 16002144
Handb Clin Neurol. 2013;116:585-98
pubmed: 24112926
Pain. 2013 Sep;154(9):1738-1742
pubmed: 23693159
Ann Neurol. 1998 Aug;44(2):209-15
pubmed: 9708543
J Neurosci. 2011 Nov 2;31(44):15650-9
pubmed: 22049408
Clin Neurophysiol. 2012 May;123(5):858-82
pubmed: 22349304
J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):353-360
pubmed: 30630956
J Neurosci. 2011 Feb 9;31(6):1937-43
pubmed: 21307231
Clin Neurophysiol. 2007 Oct;118(10):2207-14
pubmed: 17709293
Front Pharmacol. 2019 Feb 05;10:32
pubmed: 30804782
Pain. 2011 Mar;152(3 Suppl):S2-S15
pubmed: 20961685
J Physiol. 1993 Nov;471:501-19
pubmed: 8120818
Neurology. 2001;56(6 Suppl 1):S20-8
pubmed: 11294956
Br J Pharmacol. 2014 Sep;171(18):4177-92
pubmed: 24819339
Headache. 2010 Jun;50(6):921-36
pubmed: 20487038
Toxicon. 2018 Jun 1;147:120-128
pubmed: 29409817
Neurophysiol Clin. 2006 Jan-Feb;36(1):13-8
pubmed: 16530139
Brain Stimul. 2014 Mar-Apr;7(2):158-69
pubmed: 24472621
Cephalalgia. 2000 Feb;20(1):45-50
pubmed: 10817446
J Neural Transm (Vienna). 2020 Apr;127(4):567-573
pubmed: 31493094
Neurophysiol Clin. 2016 Feb;46(1):43-51
pubmed: 26924308

Auteurs

Mariarosaria Valente (M)

Clinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.
Department of Medicine, University of Udine, 33100 Udine, Italy.

Christian Lettieri (C)

Clinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.

Valentina Russo (V)

Clinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.
Intensive Rehabilitation Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.

Francesco Janes (F)

Clinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.

Gian Luigi Gigli (GL)

Clinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.
Department of Medicine, University of Udine, 33100 Udine, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH