Serum Metabolite Profiles in Participants of Lung Cancer Screening Study; Comparison of Two Independent Cohorts.
biomarkers
early detection
lung cancer
metabolomics
screening study
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
31 May 2021
31 May 2021
Historique:
received:
07
04
2021
revised:
27
05
2021
accepted:
28
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
3
6
2021
Statut:
epublish
Résumé
Serum metabolome is a promising source of molecular biomarkers that could support early detection of lung cancer in screening programs based on low-dose computed tomography. Several panels of metabolites that differentiate lung cancer patients and healthy individuals were reported, yet none of them were validated in the population at high-risk of developing cancer. Here we analyzed serum metabolome profiles in participants of two lung cancer screening studies: MOLTEST-BIS (Poland,
Identifiants
pubmed: 34072693
pii: cancers13112714
doi: 10.3390/cancers13112714
pmc: PMC8198431
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : National Science Centre, Poland
ID : 2017/27/B/NZ7/01833
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