Lutein Treatment Effects on the Redox Status and Metalloproteinase-9 (MMP-9) in Oral Cancer Squamous Cells-Are There Therapeutical Hopes?
lutein
metalloproteinase
nanoparticles
oral cancer
oxidative stress
squamous cell carcinoma
Journal
Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929
Informations de publication
Date de publication:
31 May 2021
31 May 2021
Historique:
received:
31
03
2021
revised:
27
05
2021
accepted:
28
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
3
6
2021
Statut:
epublish
Résumé
Carotenoids loaded in nanoparticles should be regarded as a promising way to increase the availability in healthy cells and to induce apoptosis in cancer. Lutein is a carotenoid that, in contrast to beta-carotene, has no known toxicities. Oral cancer represents one of the most frequent types of cancer world-wide with an incidence rate of about 9% of all types of cancer. Almost 95% of all oral cancers are represented by squamous cell carcinomas (OSCC). The aim of this study was to review and analyse the effects of lutein and Poly(d,l-lactide-co-glycolide) (PLGA) Nps containing lutein (Lut Nps) on oxidative stress biomarkers (OXSR-1, FOXO-3, TAC) and collagen degradation biomarker-MMP-9, in human cells BICR10 of buccal mucosa squamous carcinoma. Lut Nps were prepared by the emulsion-solvent evaporation method. MMP, OXSR-1, TAC, FOXO-3 and MMP-9 were measured in tumour cell lysates by the ELISA technique. Our results have shown that in Lut 100 cells and Lut Nps the OXSR1 (
Identifiants
pubmed: 34072756
pii: ma14112968
doi: 10.3390/ma14112968
pmc: PMC8199462
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Cancer Prev. 2016 Mar;21(1):13-20
pubmed: 27051644
Cancer Res. 1996 Jun 1;56(11):2484-7
pubmed: 8653681
Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15999-6004
pubmed: 25362046
Nature. 2013 Dec 12;504(7479):296-300
pubmed: 24305049
Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8204-9
pubmed: 15928081
J Immunol. 2005 Dec 15;175(12):8424-30
pubmed: 16339585
Subcell Biochem. 2016;79:359-75
pubmed: 27485230
Int J Oral Maxillofac Surg. 2004 Mar;33(2):146-9
pubmed: 15050070
Mol Cell Biol. 2003 Dec;23(23):8576-85
pubmed: 14612402
Anticancer Res. 2003 Jul-Aug;23(4):3333-9
pubmed: 12926072
J Nanobiotechnology. 2018 Sep 19;16(1):71
pubmed: 30231877
Cancer Lett. 2012 Dec 31;327(1-2):97-102
pubmed: 22178897
Nat Cell Biol. 2011 Feb;13(2):132-41
pubmed: 21258367
Oncotarget. 2018 May 4;9(34):23780-23823
pubmed: 29805774
F1000Res. 2020 Apr 2;9:229
pubmed: 32399208
Br J Cancer. 2018 Sep;119(6):724-736
pubmed: 30131545
Methods Mol Biol. 2018;1852:57-71
pubmed: 30109624
Oncotarget. 2011 Jul;2(7):562-8
pubmed: 21725138
J Biol Chem. 2009 Jun 19;284(25):17194-17205
pubmed: 19349281
Harefuah. 2017 Oct;156(10):645-649
pubmed: 29072384
Kidney Int. 2005 Jul;68(1):155-66
pubmed: 15954904
Neural Dev. 2013 Apr 25;8:7
pubmed: 23618343
Tumour Biol. 2012 Apr;33(2):287-96
pubmed: 22143938
Biosci Rep. 2016 Jun 17;36(3):
pubmed: 27129298
Cell. 2009 May 1;137(3):413-31
pubmed: 19410540
J Oncol. 2020 Jun 27;2020:9587971
pubmed: 32684934
Immunity. 2007 Feb;26(2):227-39
pubmed: 17306568
Drug Resist Updat. 2004 Apr;7(2):97-110
pubmed: 15158766
Curr Drug Targets. 2018;19(14):1696-1709
pubmed: 29577855
Clin Sci (Lond). 2015 Jun;128(12):863-75
pubmed: 25818486
Free Radic Biol Med. 2008 Apr 15;44(8):1529-35
pubmed: 18275858
Oral Oncol. 2007 Apr;43(4):321-6
pubmed: 17112772
Oncotarget. 2012 Mar;3(3):286-98
pubmed: 22410369
Clin Cancer Res. 2004 Sep 1;10(17):5820-7
pubmed: 15355912
Laryngoscope. 2002 Dec;112(12):2129-40
pubmed: 12461330
Clin Transl Med. 2017 Dec 11;6(1):44
pubmed: 29230567
Cell. 2008 Aug 8;134(3):451-60
pubmed: 18692468
Cancer Epidemiol Biomarkers Prev. 2000 Mar;9(3):257-63
pubmed: 10750663
Front Immunol. 2018 Apr 13;9:745
pubmed: 29706964
J Am Coll Nutr. 2004 Dec;23(6 Suppl):567S-587S
pubmed: 15640510
Med Oral Patol Oral Cir Bucal. 2017 May 1;22(3):e270-275
pubmed: 28160595
Nature. 1997 Sep 18;389(6648):300-5
pubmed: 9305847
J Med Food. 2015 Feb;18(2):173-81
pubmed: 25162762
Int J Biochem Cell Biol. 2008;40(11):2369-73
pubmed: 18037337
Oxid Med Cell Longev. 2016;2016:1616781
pubmed: 26881012
Mol Cell Proteomics. 2016 Mar;15(3):1032-47
pubmed: 26699800
Clin Biochem. 2017 Apr;50(6):356-363
pubmed: 27919600
Integr Cancer Ther. 2007 Dec;6(4):365-72
pubmed: 18048884
PLoS One. 2009 Nov 16;4(11):e7841
pubmed: 19924227
Biochem Biophys Res Commun. 2006 Feb 10;340(2):535-43
pubmed: 16389068
Cancer Res. 2008 Mar 15;68(6):1777-85
pubmed: 18339858
Oncol Rep. 2009 May;21(5):1223-33
pubmed: 19360298
J Nat Med. 2020 Jan;74(1):1-16
pubmed: 31588965
Food Funct. 2015 May;6(5):1518-25
pubmed: 25820747
Nat Med. 2005 Dec;11(12):1306-13
pubmed: 16286925
Molecules. 2018 Apr 14;23(4):
pubmed: 29662002
Autophagy. 2018;14(8):1467-1468
pubmed: 29938591
Eur J Cancer Prev. 2013 Jul;22(4):320-7
pubmed: 23187720
Prev Med. 1993 Sep;22(5):701-11
pubmed: 8234210
J Cell Physiol. 2020 Mar;235(3):1962-1972
pubmed: 31441032
J Dent Res. 2004 Sep;83(9):664-70
pubmed: 15329369