Operational Research to Assess the Real-Time Impact of COVID-19 on TB and HIV Services: The Experience and Response from Health Facilities in Harare, Zimbabwe.

COVID-19 EpiCollect5 HIV Harare TB treatment outcomes Zimbabwe antiretroviral therapy operational research presumptive tuberculosis tuberculosis

Journal

Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042

Informations de publication

Date de publication:
31 May 2021
Historique:
received: 29 04 2021
revised: 20 05 2021
accepted: 27 05 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 3 6 2021
Statut: epublish

Résumé

When COVID-19 was declared a pandemic, there was concern that TB and HIV services in Zimbabwe would be severely affected. We set up real-time monthly surveillance of TB and HIV activities in 10 health facilities in Harare to capture trends in TB case detection, TB treatment outcomes and HIV testing and use these data to facilitate corrective action. Aggregate data were collected monthly during the COVID-19 period (March 2020-February 2021) using EpiCollect5 and compared with monthly data extracted for the pre-COVID-19 period (March 2019-February 2020). Monthly reports were sent to program directors. During the COVID-19 period, there was a decrease in persons with presumptive pulmonary TB (40.6%), in patients registered for TB treatment (33.7%) and in individuals tested for HIV (62.8%). The HIV testing decline improved in the second 6 months of the COVID-19 period. However, TB case finding deteriorated further, associated with expiry of diagnostic reagents. During the COVID-19 period, TB treatment success decreased from 80.9 to 69.3%, and referral of HIV-positive persons to antiretroviral therapy decreased from 95.7 to 91.7%. Declining trends in TB and HIV case detection and TB treatment outcomes were not fully redressed despite real-time monthly surveillance. More support is needed to transform this useful information into action.

Identifiants

pubmed: 34072803
pii: tropicalmed6020094
doi: 10.3390/tropicalmed6020094
pmc: PMC8261627
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : World Health Organization
ID : 001
Pays : International
Organisme : Bloomberg Philanthropies through a grant with Vital Strategies and Resolve to Save Lives
ID : 78941

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Auteurs

Pruthu Thekkur (P)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
The Union South-East Asia Office, New Delhi 110016, India.

Kudakwashe C Takarinda (KC)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
AIDS and TB Department, Ministry of Health and Child Care, Causeway, Harare P.O. Box CY 1122, Zimbabwe.

Collins Timire (C)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
AIDS and TB Department, Ministry of Health and Child Care, Causeway, Harare P.O. Box CY 1122, Zimbabwe.

Charles Sandy (C)

AIDS and TB Department, Ministry of Health and Child Care, Causeway, Harare P.O. Box CY 1122, Zimbabwe.

Tsitsi Apollo (T)

AIDS and TB Department, Ministry of Health and Child Care, Causeway, Harare P.O. Box CY 1122, Zimbabwe.

Ajay M V Kumar (AMV)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
The Union South-East Asia Office, New Delhi 110016, India.
Yenepoya Medical College, Yenepoya, Mangalore 575018, India.

Srinath Satyanarayana (S)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
The Union South-East Asia Office, New Delhi 110016, India.

Hemant D Shewade (HD)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
The Union South-East Asia Office, New Delhi 110016, India.

Mohammed Khogali (M)

Special Programme for Research and Training in Tropical Disease (TDR), World Health Organization, 1211 Geneva, Switzerland.

Rony Zachariah (R)

Special Programme for Research and Training in Tropical Disease (TDR), World Health Organization, 1211 Geneva, Switzerland.

I D Rusen (ID)

Vital Strategies, New York, NY 10005, USA.

Selma Dar Berger (SD)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.

Anthony D Harries (AD)

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

Classifications MeSH