Kinetics of Neutralizing Antibodies of COVID-19 Patients Tested Using Clinical D614G, B.1.1.7, and B 1.351 Isolates in Microneutralization Assays.


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
26 05 2021
Historique:
received: 26 04 2021
revised: 21 05 2021
accepted: 24 05 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 11 6 2021
Statut: epublish

Résumé

Increasing evidence suggests that some newly emerged SARS-CoV-2 variants of concern (VoCs) resist neutralization by antibodies elicited by the early-pandemic wild-type virus. We applied neutralization tests to paired recoveree sera (

Identifiants

pubmed: 34073577
pii: v13060996
doi: 10.3390/v13060996
pmc: PMC8229637
pii:
doi:

Substances chimiques

Antibodies, Neutralizing 0
Antibodies, Viral 0
Coronavirus Nucleocapsid Proteins 0
Immunoglobulin G 0
Phosphoproteins 0
Spike Glycoprotein, Coronavirus 0
nucleocapsid phosphoprotein, SARS-CoV-2 0
spike protein, SARS-CoV-2 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Horizon 2020
ID : VEO 874735
Organisme : Jane ja Aatos Erkon Säätiö
Organisme : Helsingin ja Uudenmaan Sairaanhoitopiiri
ID : TYH2018322
Organisme : Academy of Finland

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Auteurs

Jenni Virtanen (J)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00790 Helsinki, Finland.

Ruut Uusitalo (R)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00790 Helsinki, Finland.
Department of Geosciences and Geography, Faculty of Science, University of Helsinki, 00560 Helsinki, Finland.

Essi M Korhonen (EM)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00790 Helsinki, Finland.

Kirsi Aaltonen (K)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00790 Helsinki, Finland.

Teemu Smura (T)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Suvi Kuivanen (S)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Sari H Pakkanen (SH)

Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Meilahti Infectious Diseases and Vaccine Research Center (MeiVac), Inflammation Center, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland.

Sointu Mero (S)

Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.

Anu Patjas (A)

Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Meilahti Infectious Diseases and Vaccine Research Center (MeiVac), Inflammation Center, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland.

Marianna Riekkinen (M)

Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Meilahti Infectious Diseases and Vaccine Research Center (MeiVac), Inflammation Center, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland.

Anu Kantele (A)

Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Meilahti Infectious Diseases and Vaccine Research Center (MeiVac), Inflammation Center, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland.

Visa Nurmi (V)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Klaus Hedman (K)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Virology and Immunology, Diagnostic Center, HUSLAB, Helsinki University Hospital, 00260 Helsinki, Finland.

Jussi Hepojoki (J)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Vetsuisse Faculty, Institute of Veterinary Pathology, University of Zürich, 8006 Zürich, Switzerland.

Tarja Sironen (T)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00790 Helsinki, Finland.

Eili Huhtamo (E)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00790 Helsinki, Finland.

Olli Vapalahti (O)

Department of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00790 Helsinki, Finland.
Virology and Immunology, Diagnostic Center, HUSLAB, Helsinki University Hospital, 00260 Helsinki, Finland.

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