clearance
clinical pharmacokinetics
cytochrome P450
Journal
Drug metabolism and disposition: the biological fate of chemicals
ISSN: 1521-009X
Titre abrégé: Drug Metab Dispos
Pays: United States
ID NLM: 9421550
Informations de publication
Date de publication:
01 Jun 2021
01 Jun 2021
Historique:
accepted:
15
04
2021
received:
21
12
2020
revised:
24
03
2021
pubmed:
3
6
2021
medline:
3
6
2021
entrez:
2
6
2021
Statut:
aheadofprint
Résumé
Characterizing the pharmacokinetic properties of drug candidates represents an essential task during drug development. In the past, liver microsomes and primary suspended hepatocytes have been extensively used for this purpose, but their relatively short stability limits the applicability of such
Identifiants
pubmed: 34074732
pii: dmd.120.000340
doi: 10.1124/dmd.120.000340
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited and is not used for commercial purposes.