Clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis.
Cytomegalovirus retinitis (CMVR)
laser therapy
retinal detachment
therapeutic efficacy
Journal
Quantitative imaging in medicine and surgery
ISSN: 2223-4292
Titre abrégé: Quant Imaging Med Surg
Pays: China
ID NLM: 101577942
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
entrez:
3
6
2021
pubmed:
4
6
2021
medline:
4
6
2021
Statut:
ppublish
Résumé
The aim of the present study was to evaluate the clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome (AIDS) and cytomegalovirus retinitis (CMVR). A total of 96 eyes from 80 patients with AIDS and CMVR who received anticytomegalovirus (anti-CMV) treatment in the ophthalmology and infection centers of Beijing YouAn Hospital, between June 2016 and August 2018 were retrospectively investigated. The patients were randomly divided into a nonlaser group (50 eyes from 43 patients), who were treated with anti-CMV therapy, and a laser group (46 eyes from 37 patients), who were treated with a fundus laser method to close the retinopathy area after commencing the maintenance stage of anti-CMV treatment. Both groups were followed up for 24 months. The safety of laser therapy was observed, and the efficacy of the therapy was determined by evaluating the incidence of retinal detachment. The percentage of retinal detachment in the nonlaser group was 24% compared with 6.5% in the laser group (P=0.018). There was no significant difference between the two groups in the number of CD4 The use of laser therapy in the main maintenance period of anti-CMV treatment can effectively reduce the incidence of retinal detachment in patients with AIDS and CMVR, and the therapy is safe and reliable.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of the present study was to evaluate the clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome (AIDS) and cytomegalovirus retinitis (CMVR).
METHODS
METHODS
A total of 96 eyes from 80 patients with AIDS and CMVR who received anticytomegalovirus (anti-CMV) treatment in the ophthalmology and infection centers of Beijing YouAn Hospital, between June 2016 and August 2018 were retrospectively investigated. The patients were randomly divided into a nonlaser group (50 eyes from 43 patients), who were treated with anti-CMV therapy, and a laser group (46 eyes from 37 patients), who were treated with a fundus laser method to close the retinopathy area after commencing the maintenance stage of anti-CMV treatment. Both groups were followed up for 24 months. The safety of laser therapy was observed, and the efficacy of the therapy was determined by evaluating the incidence of retinal detachment.
RESULTS
RESULTS
The percentage of retinal detachment in the nonlaser group was 24% compared with 6.5% in the laser group (P=0.018). There was no significant difference between the two groups in the number of CD4
CONCLUSIONS
CONCLUSIONS
The use of laser therapy in the main maintenance period of anti-CMV treatment can effectively reduce the incidence of retinal detachment in patients with AIDS and CMVR, and the therapy is safe and reliable.
Identifiants
pubmed: 34079729
doi: 10.21037/qims-20-990
pii: qims-11-06-2634
pmc: PMC8107343
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2634-2641Informations de copyright
2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/qims-20-990). There are no conflicts of interest to declare.
Références
Retina. 2010 Jan;30(1):42-50
pubmed: 19996825
J Pediatr Ophthalmol Strabismus. 2016 Oct 22;53:e58-e60
pubmed: 27783090
Am J Ophthalmol. 1997 Aug;124(2):227-33
pubmed: 9262548
Graefes Arch Clin Exp Ophthalmol. 2013 Jul;251(7):1829-33
pubmed: 23665863
J Med Assoc Thai. 2005 Nov;88 Suppl 9:S15-20
pubmed: 16681046
Am J Ophthalmol. 2008 Mar;145(3):397-408
pubmed: 18282490
BMC Ophthalmol. 2014 Nov 27;14:150
pubmed: 25429876
Graefes Arch Clin Exp Ophthalmol. 1998 May;236(5):359-64
pubmed: 9602320
Retina. 2006 Feb;26(2):165-9
pubmed: 16467672
Ophthalmology. 1997 Dec;104(12):2053-60; discussion 2060-1
pubmed: 9400765
Int J Ophthalmol. 2018 Oct 18;11(10):1638-1642
pubmed: 30364196
Ocul Immunol Inflamm. 2017 Aug;25(4):535-539
pubmed: 27082491
J AAPOS. 2014 Feb;18(1):78-80
pubmed: 24568990
Am J Ophthalmol. 2012 Jun;153(6):1016-24.e5
pubmed: 22310076
Zhonghua Yan Ke Za Zhi. 2005 Sep;41(9):803-6
pubmed: 16191346