Accurate assessment of coronary blood flow by continuous thermodilution technique: Validation in a swine model.
absolute coronary flow
coronary circulation
coronary microvascular resistance
Journal
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
ISSN: 1522-726X
Titre abrégé: Catheter Cardiovasc Interv
Pays: United States
ID NLM: 100884139
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
revised:
26
04
2021
received:
01
02
2021
accepted:
20
05
2021
pubmed:
4
6
2021
medline:
8
4
2022
entrez:
3
6
2021
Statut:
ppublish
Résumé
To assess the accuracy of coronary thermodilution measurements made with the RayFlow® infusion catheter. Measurements of absolute coronary blood flow (ABF) and absolute microvascular resistance (R Twelve domestic swine were instrumented with coronary flow probes placed around the left anterior descending and circumflex coronary arteries. ABF was assessed with the RayFlow® infusion catheter during continuous saline infusion at fixed rates of 5 (n = 14), 10 (n = 15), 15 (n = 19), and 20 (n = 12) ml/min. In the 60 measurements, ABF measured using thermodilution averaged 41 ± 17 ml/min (range from 17 to 90) and CBF values obtained with the coronary flow probes averaged 37 ± 18 ml/min (range from 8 to 87). The corresponding R ABF and R
Sections du résumé
OBJECTIVE
To assess the accuracy of coronary thermodilution measurements made with the RayFlow® infusion catheter.
BACKGROUND
Measurements of absolute coronary blood flow (ABF) and absolute microvascular resistance (R
METHODS
Twelve domestic swine were instrumented with coronary flow probes placed around the left anterior descending and circumflex coronary arteries. ABF was assessed with the RayFlow® infusion catheter during continuous saline infusion at fixed rates of 5 (n = 14), 10 (n = 15), 15 (n = 19), and 20 (n = 12) ml/min.
RESULTS
In the 60 measurements, ABF measured using thermodilution averaged 41 ± 17 ml/min (range from 17 to 90) and CBF values obtained with the coronary flow probes averaged 37 ± 18 ml/min (range from 8 to 87). The corresponding R
CONCLUSIONS
ABF and R
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
836-843Subventions
Organisme : École Nationale Vétérinaire d'Alfort, IMRB
ID : F-94700
Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
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Van 't Veer M, Adjedj J, Wijnbergen I, et al. Novel monorail infusion catheter for volumetric coronary blood flow measurement in humans: in vitro validation. EuroIntervention. 2016;12(6):701-707.
Xaplanteris P, Fournier S, Keulards DCJ, et al. Catheter-based measurements of absolute coronary blood flow and microvascular resistance: feasibility, safety, and reproducibility in humans. Circ Cardiovasc Interv. 2018;11(3):e006194.
De Bruyne B, Adjedj J, Xaplanteris P, et al. Saline-induced coronary hyperemia: mechanisms and effects on left ventricular function. Circ Cardiovasc Interv. 2017;10(4):e004719.
Adjedj J, Picard F, Collet C, et al. Intracoronary saline-induced hyperemia during coronary thermodilution measurements of absolute coronary blood flow: an animal mechanistic study. J Am Heart Assoc. 2020;9(15):e015793.
Everaars H dWG, Schumacher SP, Zimmermann FM, et al. Continuous thermodilution to assess absolute flow and microvascular resistance: validation in humans using [15O]H2O PET. Eur Heart J. 2019;40(28):2350-2359.