Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
03 06 2021
Historique:
received: 17 06 2020
accepted: 30 04 2021
entrez: 4 6 2021
pubmed: 5 6 2021
medline: 17 6 2021
Statut: epublish

Résumé

Due to the COVID-19 pandemic originating in China in December 2019, apart from the grave concerns on the exponentially increasing casualties, the affected countries are called to deal with severe repercussions in all aspects of everyday life, from economic recession to national and international movement restrictions. Several regions managed to handle the pandemic more successfully than others in terms of life loss, while ongoing heated debates as to the right course of action for battling COVID-19 have divided the academic community as well as public opinion. To this direction, in this paper, an autoregressive COVID-19 prediction model with heterogeneous explanatory variables for Greece is proposed, taking past COVID-19 data, non-pharmaceutical interventions (NPIs), and Google query data as independent variables, from the day of the first confirmed case-February 26th-to the day before the announcement for the quarantine measures' softening-April 24th. The analysis indicates that the early measures taken by the Greek officials positively affected the flattening of the epidemic curve, with Greece having recorded significantly decreased COVID-19 casualties per million population and managing to stay on the low side of the deaths over cases spectrum. In specific, the prediction model identifies the 7-day lag that is needed in order for the measures' results to actually show, i.e., the optimal time-intervention framework for managing the disease's spread, while our analysis also indicates an appropriate point during the disease spread where restrictive measures should be applied. Present results have significant implications for effective policy making and in the designing of the NPIs, as the second wave of COVID-19 is expected in fall 2020, and such multidisciplinary analyses are crucial in order to understand the evolution of the Daily Deaths to Daily Cases ratio along with its determinants as soon as possible, for the assessment of the respective domestic health authorities' policy interventions as well as for the timely health resources allocation.

Identifiants

pubmed: 34083549
doi: 10.1038/s41598-021-90293-5
pii: 10.1038/s41598-021-90293-5
pmc: PMC8175358
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

11741

Références

JMIR Public Health Surveill. 2020 Apr 20;6(2):e18941
pubmed: 32250957
Explor Res Hypothesis Med. 2020 Apr 18;5(2):1-6
pubmed: 32348380
JMIR Public Health Surveill. 2020 Apr 7;6(2):e18961
pubmed: 32250963
Sci Rep. 2020 Nov 26;10(1):20693
pubmed: 33244028
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
JMIR Public Health Surveill. 2019 May 29;5(2):e13439
pubmed: 31144671

Auteurs

Amaryllis Mavragani (A)

Department of Computing Science and Mathematics, Faculty of Natural Sciences, University of Stirling, Stirling, Scotland, FK9 4LA, UK. amaryllis.mavragani1@stir.ac.uk.

Konstantinos Gkillas (K)

Department of Management Science and Technology, University of Patras, Patras, Greece.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH