Bioactive α-Pyrone Derivatives from the Endophytic Fungus
Diaporthe sp.
NO
anti-inflammation
endophytic fungus
inducible nitric oxide synthase
α-pyrone
Journal
Frontiers in chemistry
ISSN: 2296-2646
Titre abrégé: Front Chem
Pays: Switzerland
ID NLM: 101627988
Informations de publication
Date de publication:
2021
2021
Historique:
received:
12
03
2021
accepted:
28
04
2021
entrez:
4
6
2021
pubmed:
5
6
2021
medline:
5
6
2021
Statut:
epublish
Résumé
Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially used in many indications, such as rheumatoid arthritis, pain, and neurodegeration. In the current study, five new compounds, including a dibenzo-α- pyrone derivative ellagic acid B (
Identifiants
pubmed: 34084766
doi: 10.3389/fchem.2021.679592
pii: 679592
pmc: PMC8167431
doi:
Types de publication
Journal Article
Langues
eng
Pagination
679592Informations de copyright
Copyright © 2021 Pu, Liu, Wang, Peng, Zheng, Tang, Hui, Nie, Huang, Duan and Huang.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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