Computed tomography-guided microwave ablation of perivascular liver metastases from colorectal cancer: a study of the ablation zone, feasibility, and safety.


Journal

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
ISSN: 1464-5157
Titre abrégé: Int J Hyperthermia
Pays: England
ID NLM: 8508395

Informations de publication

Date de publication:
2021
Historique:
entrez: 4 6 2021
pubmed: 5 6 2021
medline: 6 7 2021
Statut: ppublish

Résumé

To compare the ablation margins and safety of microwave ablation (MWA) of perivascular versus non-perivascular liver metastases from colorectal cancer (CRC) and to determine the risk factors for local tumor progression (LTP) after perivascular MWA. Between June 2017 and June 2019, 84 metastases were treated: 39 perivascular (<5 mm from a vessel >3 mm), and 46 non-perivascular. Perivascular metastases were treated with either conventional or optimized protocols (maximum power and/or several heating cycles after repositioning the needle regardless of the initial tumor dimensions). The mean diameter of metastases was 15.4 mm (SD: 7.56). Vascular proximity did not result in a significant difference in ablation margins. The technical success rate, primary efficacy, and secondary efficacy were 90%, 66%, and 83%, respectively. Perivascular location was not a risk factor for time to LTP ( MWA is an effective and safe treatment for perivascular liver metastases from CRC, provided that satisfactory margins are achieved. A maximalist attitude could be related to better local control.

Identifiants

pubmed: 34085891
doi: 10.1080/02656736.2021.1912413
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

887-899

Auteurs

Jean Izaaryene (J)

Department of Radiology, Institut Paoli Calmettes, Aix Marseille University, Marseille, France.

Maxime Drai (M)

Department of Radiology, Institut Paoli Calmettes, Aix Marseille University, Marseille, France.

Cécile Deniel (C)

Department of Radiology, Institut Paoli Calmettes, Aix Marseille University, Marseille, France.

Pauline Bridge (P)

Laboratoire Imagerie Interventionnelle Experimentale CERIMED, Marseille, France.

Geoffrey Rico (G)

Department of Radiology, Institut Paoli Calmettes, Aix Marseille University, Marseille, France.

Nassima Daidj (N)

Department of Radiology, Institut Paoli Calmettes, Aix Marseille University, Marseille, France.

Marine Gilabert (M)

Department of Oncology, Institut Paoli Calmettes, Marseille, France.

Jacques Ewald (J)

Department of Surgery, Institut Paoli Calmettes, Marseille, France.

Olivier Turrini (O)

Department of Surgery, Institut Paoli Calmettes, Marseille, France.

Gilles Piana (G)

Department of Radiology, Institut Paoli Calmettes, Aix Marseille University, Marseille, France.

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Classifications MeSH