Imaging Features of Pulmonary Immune-related Adverse Events.
CTLA-4 antigen
Drug-related side effects and adverse reactions
Immunotherapy
Pneumonitis
Programmed cell death 1 receptor
Journal
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
ISSN: 1556-1380
Titre abrégé: J Thorac Oncol
Pays: United States
ID NLM: 101274235
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
31
07
2020
revised:
05
03
2021
accepted:
16
05
2021
pubmed:
5
6
2021
medline:
15
9
2021
entrez:
4
6
2021
Statut:
ppublish
Résumé
Pulmonary immune-related adverse events represent rare but potentially severe side effects of immunotherapies. Diagnosis is often challenging, as symptoms and imaging features are not specific and may mimic other lung diseases, thus potentially delaying appropriate patient management. In this setting, an accurate imaging evaluation is essential for a prompt detection and correct management of these drug-induced lung diseases. The purpose of this article is to review the different types of pulmonary immune-related adverse events, describe their imaging characteristics on both high-resolution computed tomography and positron emission tomography/computed tomography and stress their underlying diagnostic challenge by presenting the mimickers.
Identifiants
pubmed: 34087477
pii: S1556-0864(21)02188-2
doi: 10.1016/j.jtho.2021.05.017
pii:
doi:
Substances chimiques
CTLA-4 Antigen
0
Programmed Cell Death 1 Receptor
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1449-1460Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2021 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.