Prospective observational cohort study on epidemiology, treatment and outcome of patients with traumatic brain injury (TBI) in German BG hospitals.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
04 06 2021
Historique:
entrez: 5 6 2021
pubmed: 6 6 2021
medline: 22 6 2021
Statut: epublish

Résumé

Since 2000/2001, no large-scale prospective studies addressing traumatic brain injury (TBI) epidemiology in Germany have been published. Our aim was to look for a possible shift in TBI epidemiology described in other European countries, to look for possible changes in TBI management and to identify predictors of 1-year outcome especially in patients with mild TBI. Observational cohort study. All patients suffering from a TBI of any degree between 1 October 2014 and 30 September 2015, and who arrived in one of the seven participating BG hospitals within 24 hours after trauma, were included. In total, 3514 patients were included. Initial care, acute hospital care and rehabilitation were documented using standardised documentation forms. A standardised telephone interview was conducted 3 and 12 months after TBI in order to obtain information on outcome. Peaks were identified in males in the early 20s and mid-50s, and in both sexes in the late 70s, with 25% of all patients aged 75 or older. A fall was the most frequent cause of TBI, followed by traffic accidents (especially bicyclists). The number of head CT scans increased, and the number of conventional X-rays of the skull decreased compared with 2000/2001. Besides, more patients were offered rehabilitation than before. Though most TBI were classified as mild, one-third of the patients participating in the telephone interview after 12 months still reported troubles attributed to TBI. Negative predictors in mild TBI were female gender, intracranial bleeding and Glasgow Coma Scale (GCS) 13/14. The observed epidemiologic shift in TBI (ie, elderly patients, more falls, more bicyclists) calls for targeted preventive measures. The heterogeneity behind the diagnosis 'mild TBI' emphasises the need for defining subgroups not only based on GCS.

Identifiants

pubmed: 34088707
pii: bmjopen-2020-045771
doi: 10.1136/bmjopen-2020-045771
pmc: PMC8183205
doi:

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e045771

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Peter Schwenkreis (P)

Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr-University Bochum, Bochum, Germany peter.schwenkreis@rub.de.

Andreas Gonschorek (A)

Neurology, Berufsgenossenschaftliches Klinikum Hamburg, Hamburg, Germany.

Florian Berg (F)

Neurosurgery, Berufsgenossenschaftliches Klinikum Unfallkrankenhaus Berlin, Berlin, Germany.

Ullrich Meier (U)

Neurosurgery, Berufsgenossenschaftliches Klinikum Unfallkrankenhaus Berlin, Berlin, Germany.

Witold Rogge (W)

Neurology, Berufsgenossenschaftliches Klinikum Unfallkrankenhaus Berlin, Berlin, Germany.

Ingo Schmehl (I)

Neurology, Berufsgenossenschaftliches Klinikum Unfallkrankenhaus Berlin, Berlin, Germany.

Bodo Christian Kern (BC)

Neurosurgery, Berufsgenossenschaftliches Klinikum Bergmannstrost Halle, Halle, Germany.

Hans-Jörg Meisel (HJ)

Neurosurgery, Berufsgenossenschaftliches Klinikum Bergmannstrost Halle, Halle, Germany.

Kai Wohlfarth (K)

Neurology, Berufsgenossenschaftliches Klinikum Bergmannstrost Halle, Halle, Germany.

Stefan Gross (S)

Neurology, Berufsgenossenschaftliches Klinikum Hamburg, Hamburg, Germany.

Matthias Sczesny-Kaiser (M)

Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr-University Bochum, Bochum, Germany.

Martin Tegenthoff (M)

Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr-University Bochum, Bochum, Germany.

Jürgen Boschert (J)

Neurosurgery, Berufsgenossenschaftliche Unfallklinik Ludwigshafen, Ludwigshafen, Germany.

Ralf Bruckmoser (R)

Neurosurgery, Berufsgenossenschaftliche Unfallklinik Murnau, Murnau, Germany.

Andrea Fürst (A)

Neurology, Berufsgenossenschaftliche Unfallklinik Murnau, Murnau, Germany.

Marc Schaan (M)

Neurorehabilitation, Berufsgenossenschaftliche Unfallklinik Murnau, Murnau, Germany.

Martin Strowitzki (M)

Neurosurgery, Berufsgenossenschaftliche Unfallklinik Murnau, Murnau, Germany.

Andreas Pingel (A)

Neurosurgery, Berufsgenossenschaftliche Unfallklinik Frankfurt am Main, Frankfurt am Main, Germany.

Lisa Linnea Jägers (LL)

Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr-University Bochum, Bochum, Germany.

Henrik Rudolf (H)

Medical Informatics, Biometry and Epidemiology, Ruhr-University Bochum, Bochum, Germany.

Hans-Joachim Trampisch (HJ)

Medical Informatics, Biometry and Epidemiology, Ruhr-University Bochum, Bochum, Germany.

Johannes Lemcke (J)

Neurosurgery, Berufsgenossenschaftliches Klinikum Unfallkrankenhaus Berlin, Berlin, Germany.

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