A case report of prostate cancer with leptomeningeal metastasis.
leptomeningeal carcinomatosis
prostate cancer
Journal
Cancer reports (Hoboken, N.J.)
ISSN: 2573-8348
Titre abrégé: Cancer Rep (Hoboken)
Pays: United States
ID NLM: 101747728
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
revised:
18
05
2021
received:
05
05
2021
accepted:
19
05
2021
pubmed:
6
6
2021
medline:
9
8
2022
entrez:
5
6
2021
Statut:
ppublish
Résumé
Prostate cancer is the most prevalent cancer in men. However, leptomeningeal involvement by prostate carcinoma is a rare event. Here, we report a 69-year-old patient with castration-resistant metastatic prostate cancer who presented with headache and ataxia. Brain MRI revealed a huge invasive interaxial mass at right occipital lobe with diffuse thickening and enhancement of meninges, the arachnoid, and the pia mater, and he was diagnosed with leptomeningeal carcinomatosis. The patient received whole brain radiotherapy. Despite the fact that brain and leptomeningeal metastases are not very common in patients with prostate cancer, signs and symptoms of nervous system disorders should be assessed carefully, and consideration of such unusual metastases must be considered.
Sections du résumé
BACKGROUND
Prostate cancer is the most prevalent cancer in men. However, leptomeningeal involvement by prostate carcinoma is a rare event.
CASE
Here, we report a 69-year-old patient with castration-resistant metastatic prostate cancer who presented with headache and ataxia. Brain MRI revealed a huge invasive interaxial mass at right occipital lobe with diffuse thickening and enhancement of meninges, the arachnoid, and the pia mater, and he was diagnosed with leptomeningeal carcinomatosis. The patient received whole brain radiotherapy.
CONCLUSION
Despite the fact that brain and leptomeningeal metastases are not very common in patients with prostate cancer, signs and symptoms of nervous system disorders should be assessed carefully, and consideration of such unusual metastases must be considered.
Identifiants
pubmed: 34089302
doi: 10.1002/cnr2.1463
pmc: PMC9351675
doi:
Types de publication
Case Reports
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1463Informations de copyright
© 2021 The Authors. Cancer Reports published by Wiley Periodicals LLC.
Références
Med Oncol. 2013 Mar;30(1):429
pubmed: 23292836
J Clin Oncol. 2008 Jul 1;26(19):3281-4
pubmed: 18591564
Cancer. 2018 Jan 1;124(1):21-35
pubmed: 29165794
Cancer. 1984 Jun 15;53(12):2728-30
pubmed: 6722732
Cancer Invest. 2005;23(2):145-54
pubmed: 15813508
Rev Urol. 2020;22(2):80-84
pubmed: 32760233
J Med Imaging Radiat Oncol. 2008 Aug;52(4):376-81
pubmed: 18811763
Oncotarget. 2017 Aug 16;8(42):73312-73328
pubmed: 29069871
Cancer Rep (Hoboken). 2022 Aug;5(8):e1463
pubmed: 34089302
Case Rep Oncol. 2019 Apr 10;12(1):311-316
pubmed: 31123457
Clin Exp Metastasis. 2010;27(1):19-23
pubmed: 19904616
J Neurooncol. 2012 Mar;107(1):191-6
pubmed: 21989810
Cancer Treat Rev. 1999 Apr;25(2):103-19
pubmed: 10395835
Cancer. 1998 Feb 15;82(4):733-9
pubmed: 9477107
Surg Neurol. 2006 Apr;65(4):372-5, discussion 375-6
pubmed: 16531199