Predictive Fat Mass Equations for Children With Inflammatory Bowel Disease.
Journal
Journal of pediatric gastroenterology and nutrition
ISSN: 1536-4801
Titre abrégé: J Pediatr Gastroenterol Nutr
Pays: United States
ID NLM: 8211545
Informations de publication
Date de publication:
01 10 2021
01 10 2021
Historique:
pubmed:
7
6
2021
medline:
25
2
2023
entrez:
6
6
2021
Statut:
ppublish
Résumé
Evaluate accuracy of skinfold thicknesses and body mass index (BMI) for the prediction of fat mass percentage (FM%) in paediatric inflammatory bowel disease (IBD) and to develop population-specific formulae based on anthropometry for estimation of FM%. IBD children (n = 30) and healthy controls (HCs, n = 144) underwent anthropometric evaluation and dual-energy X-ray absorptiometry (DEXA) scan, as the clinical reference for measurement of body composition. Body FM% estimated with skinfolds thickness was compared with FM% measured with DEXA. By means of 4 prediction models, population specific formulae for estimation of FM% were developed. No significant difference in terms of FM% measured by DEXA was found between IBD population and HCs (FM% 29.6% vs 32.2%, P = 0.108). Triceps skinfold thickness (TSF, Model 2) was better than BMI (Model 1) at predicting FM% (82% vs 68% of variance). The sum of 2 skinfolds (biceps + triceps; SF2, Model 3) showed an improvement in the prediction of FM% as compared with TSF, Model 2 (86% vs 82% of variance). The sum of 4 skinfolds (biceps + triceps + suprailiac + subscapular; Model 4) showed further improvement in the prediction of FM% as compared with SF2 (88% vs 86% of variance). The sum of 4 skinfolds is the most accurate in predicting FM% in paediatric IBD. The sum of 2 skinfolds is less accurate but more feasible and less prone to error. The newly developed population-specific formulae could be a valid tool for estimation of body composition in IBD population and an alternative to DEXA measurement.
Identifiants
pubmed: 34091539
doi: 10.1097/MPG.0000000000003188
pii: 00005176-202110000-00024
pmc: PMC10237347
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e98-e104Informations de copyright
Copyright © 2021 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
Références
De Mesquita MB, Civitelli F, Levine A, et al. Epidemiology, genes and inflammatory bowel diseases in childhood. Dig Liver Dis 2007; 40:3–11.
Ng SC, Shi HY, Hamidi N, et al. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies. Lancet 2017; 390:2769–2778.
Miller T, Suskind LD. Exclusive enteral nutrition in pediatric inflammatory bowel disease. Curr Opin Pediatr 2018; 30:671–676.
Levine A, Wine E, Assa A, et al. Crohn's disease exclusion diet plus partial enteral nutrition induces sustained remission in a randomized controlled trial. Gastroenterology 2019; 157:440.e8–450.e8.
Miele E, Shamir R, Aloi M, et al. Nutrition in pediatric inflammatory bowel disease: a position paper on behalf of the Porto Inflammatory Bowel Disease Group of the European Society of Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 2018; 66:687–708.
Hill RJ. Update on nutritional status, body composition and growth in paediatric inflammatory bowel disease. World J Gastroenterol 2014; 20:3191–3197.
Callias C, Ezri J, Marques-Vidal PM, et al. Assessment of skinfold thickness equations in estimating body composition in children with inflammatory bowel disease. J Paediatr Child Health 2016; 52:547–555.
Turner D, Ruemmele FM, Orlanski-Meyer E, et al. Management of paediatric ulcerative colitis, part 1: ambulatory care—an evidence-based guideline from European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 2018; 67:257–291.
Kappelman MD, Crandall WV, Colletti RB, et al. A Short Pediatric Crohn's Disease Activity Index for Quality Improvement and Observational Research. Inflamm Bowel Dis 2011; 17:112–117.
Marshall WA, Tanner JM. Variations in the pattern of pubertal changes in boys. Arch Dis Child 1970; 45:13–23.
Marshall WA, Tanner JM. Variations in pattern of pubertal changes in girls. Arch Dis Child 1969; 44:291–303.
WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards based on length/height, weight and age. Acta Paediatr Suppl 2006; 450:76–85.
Cole TJ, Bellizzi MC, Flegal KM, et al. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000; 320:1240–1243.
Lohman TG, Roche AF, Martorell R. Anthropometric Standardization Reference Manual. Champaign, IL: Human Kinetics Books; 1988.
Brook CG. Determination of body composition of children from skinfold measurements. Arch Dis Child 1971; 46:182–184.
Johnston JL, Leong MS, Checkland EG, et al. Body fat assessed from body density and estimated from skinfold thickness in normal children and children with cystic fibrosis. Am J Clin Nutr 1998; 48:1362–1364.
Durnin JV, Rahaman MM. The assessment of the amount of fat in the human body from measurements of skinfold thickness. Br J Nutr 1967; 21:681–689.
Durnin JV, Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 1974; 32:77–97.
Siri WE. Body composition from fluid spaces and density: analysis of methods. In Techniques for Measuring Body Composition eds J Brozek and A Henschel, pp 223-234. Washingthon, DC: National Academy of Sciences.
Kriemler S, Puder J, Zahner L, et al. Estimation of percentage body fat in 6- to 13 year-old children by skinfold thickness, body mass index and waist circumference. Br J Nutr 2010; 104:1565–1572.
Royston P, Sauerbrei W. Multivariable Model-building: A Pragmatic Approach to Regression Analysis Based on Fractional Polynomials for Modelling Continuous Variables. Chichester: John Wiley; 2008.
Weisberg S. Applied Linear Regression. Hoboken: Wiley; 2014.
Efron B. An Introduction to the Bootstrap. Boca Raton: Chapman & Hall/CRC; 1994.
Springer International Publishing, Harrell F. Regression Modeling Strategies. 2015.
Sentongo TA, Semeo EJ, Piccoli DA, et al. Growth, body composition, and nutritional status in children and adolescents with Crohn's disease. J Pediatr Gastroenterol Nutr 2000; 31:33–40.
Varille V, Cezard JP, de Lagausie P, et al. Resting energy expenditure before and after surgical resection of gut lesions in pediatric Crohn's disease. J Pediatr Gastroenterol Nutr 1996; 23:13–19.
Thayu M, Shults J, Burnham JM, et al. Gender differences in body composition deficits at diagnosis in children and adolescents with Crohn's disease. Inflamm Bowel Dis 2007; 13:1121–1128.
Zoli G, Katelaris PH, Garrow J, et al. Increased energy expenditure in growing adolescents with Crohn's disease. Dig Dis Sci 1996; 41:1754–1759.
Azcue M, Rashid M, Griffiths A, et al. Energy expenditure and body composition in children with Crohn's disease: effect of enteral nutrition and treatment with prednisolone. Gut 1997; 41:203–208.
Forbes A, Escher J, Hébuterne X, et al. ESPEN guideline: clinical nutrition in inflammatory bowel disease. Clin Nutr 2017; 36:321–347.
Thangarajah D, Hyde MJ, Konteti VKS, et al. Systematic review: body composition in children with inflammatory bowel disease. Aliment Pharmacol Ther 2015; 42:142–157.
Thayu M, Denson LA, Shults J, et al. Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease. Gastroenterology 2010; 139:430–438.
Burnham JM, Shults J, Semeao E, et al. Body composition alterations consistent with cachexia in children and young adults with Crohn disease. Am J Clin Nutr 2005; 82:413–420.
Boot AM, Bouquet J, Krenning EP, et al. Bone mineral density and nutritional status in children with chronic inflammatory bowel disease. Gut 1998; 42:188–194.
Laakso S, Valta H, Verkasalo M, et al. Impaired bone health in inflammatory bowel disease: a case-control study in 80 pediatric patients. Calcif Tissue Int 2012; 91:121–130.
Burnham JM, Shults J, Semeao E, et al. Whole body BMC in pediatric Crohn disease: independent effects of altered growth, maturation, and body composition. J Bone Miner Res 2004; 19:1961–1968.
Tsiountsioura M, Wong JE, Upton J, et al. Detailed assessment of nutritional status and eating patterns in children with gastrointestinal diseases attending an out patients clinic and contemporary healthy controls. Eur J Clin Nutr 2014; 68:700–706.
Gerasimidis K, Talwar D, Duncan A, et al. Impact of exclusive enteral nutrition on body composition and circulating micronutrients in plasma and erythrocytes of children with active Crohn's disease. Inflamm Bowel Dis 2012; 18:1672–1681.
Santos JCD, Malaguti C, Lucca FA, et al. Impact of biological therapy on body composition of patients with Crohn's disease. Rev Assoc Med Bras 2017; 63:407–413.
Dhaliwal J, Martincevic I, Williams B, et al. Body composition using air displacement plethysmography in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2020; 71:52–58.
Mazhar F, Battini V, Pozzi M, et al. Changes in anthropometric parameters after anti-TNFα therapy in inflammatory bowel disease: a systematic review and meta-analysis. BioDrugs 2020; 34:649–668.