Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study.

Case report Pharmacokinetics Testosterone pellets Testosterone replacement therapy

Journal

Urology case reports
ISSN: 2214-4420
Titre abrégé: Urol Case Rep
Pays: United States
ID NLM: 101626357

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 24 04 2021
accepted: 10 05 2021
entrez: 7 6 2021
pubmed: 8 6 2021
medline: 8 6 2021
Statut: epublish

Résumé

We present a patient receiving Testopel® implants whose serum testosterone levels, as measured by a CDC certified assay, were accurately predicted by a multi-compartmental model. This is the first time a model has predicted measured serum testosterone levels within 4% of values calculated. To our knowledge, it was also the first time a pharmacokinetic model allowed patient targeted serum levels (peak/trough/average) to be reached within three months.

Identifiants

pubmed: 34094874
doi: 10.1016/j.eucr.2021.101714
pii: S2214-4420(21)00154-6
pmc: PMC8165545
doi:

Types de publication

Case Reports

Langues

eng

Pagination

101714

Informations de copyright

© 2021 Published by Elsevier Inc.

Références

Clin Endocrinol (Oxf). 2013 Feb;78(2):291-6
pubmed: 22804876

Auteurs

David Seitman (D)

3 Cara Ct., Northfield, NJ, 08225, USA.

Joseph Fallon (J)

Department of Medicine at Rowan University in Sewell, NJ, USA.

Barry Kimmels (B)

Chief of Division of Urology at Cape Regional Medical Center in Cape May, Courthouse, NJ, USA.

Classifications MeSH