Prevalence of Angina Among Primary Care Patients With Coronary Artery Disease.


Journal

JAMA network open
ISSN: 2574-3805
Titre abrégé: JAMA Netw Open
Pays: United States
ID NLM: 101729235

Informations de publication

Date de publication:
01 06 2021
Historique:
entrez: 7 6 2021
pubmed: 8 6 2021
medline: 8 1 2022
Statut: epublish

Résumé

Angina pectoris is associated with morbidity and mortality. Angina prevalence and frequency among contemporary US populations with coronary artery disease (CAD) remain incompletely defined. To ascertain the angina prevalence and frequency among stable outpatients with CAD. This cross-sectional survey study involved telephone-based administration of the Seattle Angina Questionnaire-7 (SAQ-7) between February 1, 2017, and July 31, 2017, to a nonconvenience sample of adults with established CAD who receive primary care through a large US integrated primary care network. Data analysis was performed from August 2017 to August 2019. SAQ-7 administration. Angina prevalence and frequency were assessed using SAQ-7 question 2. Covariates associated with angina were assessed in univariable and multivariable regression. Of 4139 eligible patients, 1612 responded to the survey (response rate, 38.9%). The mean (SD) age of the respondents was 71.8 (11.0) years, 577 (35.8%) were women, 1447 (89.8%) spoke English, 147 (9.1%) spoke Spanish, 1336 (82.8%) were White, 76 (4.7%) were Black, 92 (5.7%) were Hispanic, 974 (60.4%) had Medicare, and 83 (5.2%) had Medicaid. Among respondents, 342 (21.2%) reported experiencing angina at least once monthly; among those, 201 (12.5%) reported daily or weekly angina, and 141 respondents (8.7%) reported monthly angina. The mean (SD) SAQ-7 score was 93.7 (13.7). After multivariable adjustment, speaking a language other than Spanish or English (odds ratio [OR], 5.07; 95% CI, 1.39-18.50), Black race (OR, 2.01; 95% CI, 1.08-3.75), current smoking (OR, 1.88; 95% CI, 1.27-2.78), former smoking (OR, 1.69; 95% CI, 1.13-2.51), atrial fibrillation (OR, 1.52; 95% CI, 1.02-2.26), and chronic obstructive pulmonary disease (OR, 1.61; 95% CI, 1.18-2.18) were associated with more frequent angina. Male sex (OR, 0.63; 95% CI, 0.47-0.86), peripheral artery disease (OR, 0.63; 95% CI, 0.44-0.90), and novel oral anticoagulant use (OR, 0.19; 95% CI, 0.08-0.48) were associated with less frequent angina. Among stable outpatients with CAD receiving primary care through an integrated primary care network, 21.2% of surveyed patients reported experiencing angina at least once monthly. Several objective demographic and clinical characteristics were associated with angina frequency. Proactive assessment of angina symptoms using validated assessment tools and estimation of patients at higher risk of suboptimally controlled angina may be associated with reduced morbidity.

Identifiants

pubmed: 34097047
pii: 2780703
doi: 10.1001/jamanetworkopen.2021.12800
pmc: PMC8185599
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2112800

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Auteurs

Daniel M Blumenthal (DM)

Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston.
Harvard Medical School, Boston, Massachusetts.
Coeur Value, LLC, Wellesley, Massachusetts.

Sidney E Howard (SE)

Mongan Institute, Massachusetts General Hospital, Boston.

Jennifer Searl Como (J)

Massachusetts General Physicians Organization, Massachusetts General Hospital, Boston.

Sandra M O'Keefe (SM)

Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston.

Steven J Atlas (SJ)

Harvard Medical School, Boston, Massachusetts.
Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston.

Daniel M Horn (DM)

Harvard Medical School, Boston, Massachusetts.
Massachusetts General Physicians Organization, Massachusetts General Hospital, Boston.
Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston.

Neil W Wagle (NW)

Harvard Medical School, Boston, Massachusetts.
Devoted Health, Waltham, Massachusetts.
Division of General Internal Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Jason H Wasfy (JH)

Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston.
Harvard Medical School, Boston, Massachusetts.
Massachusetts General Physicians Organization, Massachusetts General Hospital, Boston.

Robert W Yeh (RW)

Harvard Medical School, Boston, Massachusetts.
Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Cardiology Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

Joshua P Metlay (JP)

Harvard Medical School, Boston, Massachusetts.
Mongan Institute, Massachusetts General Hospital, Boston.
Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston.

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