A case of lymphocytic esophagitis in a woman with multiple allergies.

Allergy Dysphagia Endoscopy Eosinophilic esophagitis GERD Lymphocytic esophagitis

Journal

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
ISSN: 1710-1484
Titre abrégé: Allergy Asthma Clin Immunol
Pays: England
ID NLM: 101244313

Informations de publication

Date de publication:
07 Jun 2021
Historique:
received: 03 11 2020
accepted: 18 05 2021
entrez: 8 6 2021
pubmed: 9 6 2021
medline: 9 6 2021
Statut: epublish

Résumé

Lymphocytic esophagitis is a newly recognized entity of unknown origin. Dysphagia is defined as difficulty swallowing and represents a common symptom in the general population with a prevalence of approximately 20%. Chronic inflammation of the esophageal wall may manifest itself clinically and endoscopically, mimicking inflammation of another origin. However, little is known about the pathogenesis of the disease, as patients are seldom suspected and rarely diagnosed with lymphocytic esophagitis. Here, we present a rare case of lymphocytic esophagitis in a patient with multiple allergies and suspected eosinophilic esophagitis. A 28-year-old woman with polyvalent sensitization to food and inhalant allergens presented with intermittent dysphagia, a sensation of a foreign body in the throat, itchiness of the oral cavity after ingesting certain foods, heartburn, and prolonged chewing time. A skin prick test showed positive results for birch-tree, alder, hazel, and rye pollen, as well as house dust mites. Apart from obesity (BMI 30 kg/m In summary, this clinical case illustrates that lymphocytic esophagitis, as a newly recognized entity, should be considered in the differential diagnosis of chronic dysphagia. Additionally, when treating allergic patients, clinicians should be aware that lymphocytic esophagitis, distinct from eosinophilic esophagitis, should be considered in the diagnosis of patients with atopy and upper gastrointestinal symptoms.

Sections du résumé

BACKGROUND BACKGROUND
Lymphocytic esophagitis is a newly recognized entity of unknown origin. Dysphagia is defined as difficulty swallowing and represents a common symptom in the general population with a prevalence of approximately 20%. Chronic inflammation of the esophageal wall may manifest itself clinically and endoscopically, mimicking inflammation of another origin. However, little is known about the pathogenesis of the disease, as patients are seldom suspected and rarely diagnosed with lymphocytic esophagitis.
CASE PRESENTATION METHODS
Here, we present a rare case of lymphocytic esophagitis in a patient with multiple allergies and suspected eosinophilic esophagitis. A 28-year-old woman with polyvalent sensitization to food and inhalant allergens presented with intermittent dysphagia, a sensation of a foreign body in the throat, itchiness of the oral cavity after ingesting certain foods, heartburn, and prolonged chewing time. A skin prick test showed positive results for birch-tree, alder, hazel, and rye pollen, as well as house dust mites. Apart from obesity (BMI 30 kg/m
CONCLUSIONS CONCLUSIONS
In summary, this clinical case illustrates that lymphocytic esophagitis, as a newly recognized entity, should be considered in the differential diagnosis of chronic dysphagia. Additionally, when treating allergic patients, clinicians should be aware that lymphocytic esophagitis, distinct from eosinophilic esophagitis, should be considered in the diagnosis of patients with atopy and upper gastrointestinal symptoms.

Identifiants

pubmed: 34099042
doi: 10.1186/s13223-021-00558-x
pii: 10.1186/s13223-021-00558-x
pmc: PMC8186211
doi:

Types de publication

Journal Article

Langues

eng

Pagination

56

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Auteurs

O Wojas (O)

Department of Prevention of Environmental Hazard and Allergology, Medical University of Warsaw, Warsaw, Poland.

M Żalikowska-Gardocka (M)

Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland. mzalikowska.wum@gmail.com.

E Krzych-Fałta (E)

Department of Prevention of Environmental Hazard and Allergology, Medical University of Warsaw, Warsaw, Poland.

B Szczepankiewicz (B)

Department of Pathomorphology, Medical University of Warsaw, Warsaw, Poland.

P Samel-Kowalik (P)

Department of Prevention of Environmental Hazard and Allergology, Medical University of Warsaw, Warsaw, Poland.

B Samoliński (B)

Department of Prevention of Environmental Hazard and Allergology, Medical University of Warsaw, Warsaw, Poland.

A Przybyłkowski (A)

Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.

Classifications MeSH