VICTORIA: VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms.
Hemodynamics
Intracranial aneurysm
Neck curve
Rupture risk assessment
VICTORIA
Journal
Cardiovascular engineering and technology
ISSN: 1869-4098
Titre abrégé: Cardiovasc Eng Technol
Pays: United States
ID NLM: 101531846
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
received:
06
10
2020
accepted:
17
03
2021
pubmed:
9
6
2021
medline:
26
10
2021
entrez:
8
6
2021
Statut:
ppublish
Résumé
For the status evaluation of intracranial aneurysms (IAs), morphological and hemodynamic parameters can provide valuable information. For their extraction, a separation of the aneurysm sac from its parent vessel is required that yields the neck curve and the ostium. However, manual and subjective neck curve and ostium definitions might lead to inaccurate IA assessments. The research project VICTORIA was initiated, allowing users to interactively define the neck curve of five segmented IA models using a web application. The submitted results were qualitatively and quantitatively compared to identify the minimum, median and maximum aneurysm surface area. Finally, image-based blood flow simulations were carried out to assess the effect of variable neck curve definitions on relevant flow- and shear-related parameters. In total, 55 participants (20 physicians) from 18 countries participated in VICTORIA. For relatively simple aneurysms, a good agreement with respect to the neck curve definition was found. However, differences among the participants increased with increasing complexity of the aneurysm. Furthermore, it was observed that the majority of participants excluded any small arteries occurring in the vicinity of an aneurysm. This can lead to non-negligible deviations among the flow- and shear-related parameters, which need to be carefully evaluated, if quantitative analysis is desired. Finally, no differences between participants with medical and non-medical background could be observed. VICTORIAs findings reveal the complexity of aneurysm neck curve definition, especially for bifurcation aneurysms. Standardization appears to be mandatory for future sac-vessel-separations. For hemodynamic simulations a careful neck curve definition is crucial to avoid inaccuracies during the quantitative flow analysis.
Identifiants
pubmed: 34100225
doi: 10.1007/s13239-021-00535-w
pii: 10.1007/s13239-021-00535-w
pmc: PMC8354974
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
454-465Subventions
Organisme : Deutsche Forschungsgemeinschaft (DE)
ID : SA 3461/2-1
Organisme : Deutsche Forschungsgemeinschaft
ID : BE 6230/2-1
Organisme : Bundesministerium für Bildung und Forschung
ID : 13GW0473A
Informations de copyright
© 2021. The Author(s).
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