Enhanced autophagy in
Aging
beclin 1 mutant mouse
increased autophagy
neural stem cells
neurogenesis
self-renewal
Journal
Autophagy
ISSN: 1554-8635
Titre abrégé: Autophagy
Pays: United States
ID NLM: 101265188
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
pubmed:
9
6
2021
medline:
27
4
2022
entrez:
8
6
2021
Statut:
ppublish
Résumé
Macroautophagy/autophagy is emerging as a major pathway that regulates both aging and stem cell function. Previous studies have demonstrated a positive correlation of autophagy with longevity; however, these studies did not directly address the consequence of altered autophagy in stem cells during aging. In this study, we used
Identifiants
pubmed: 34101533
doi: 10.1080/15548627.2021.1936358
pmc: PMC8942493
doi:
Substances chimiques
Beclin-1
0
Becn1 protein, mouse
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
409-422Subventions
Organisme : NCI NIH HHS
ID : R01 CA211066
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL073394
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS094144
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS103981
Pays : United States
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