Characterization of ABH-subtype donor-specific antibodies in ABO-A-incompatible kidney transplantation.
ABO incompatibility
antibody biology
antigen biology
clinical research/practice
glycomics
histocompatibility
kidney transplantation/nephrology
translational research/science
Journal
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
30
04
2021
received:
16
07
2020
accepted:
15
05
2021
pubmed:
9
6
2021
medline:
12
11
2021
entrez:
8
6
2021
Statut:
ppublish
Résumé
ABO-incompatible (ABOi) transplantation requires preemptive antibody reduction; however, the relationship between antibody-mediated rejection (AMR) and ABO-antibodies, quantified by hemagglutination (HA), is inconsistent, possibly reflecting variable graft resistance to AMR or HA assay limitations. Using an ABH-glycan microarray, we quantified ABO-A antigen-subtype (A-subtype)-specific IgM and IgG in 53 ABO-O recipients of ABO-A kidneys, before and after antibody removal (therapeutic plasma exchange [TPE] or ABO-A-trisaccharide immunoadsorption [IA]) and 1-year posttransplant. IgM binding to all A-subtypes correlated highly (R
Identifiants
pubmed: 34101982
doi: 10.1111/ajt.16712
pmc: PMC8597088
pii: S1600-6135(22)08797-4
doi:
Substances chimiques
ABO Blood-Group System
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3649-3662Subventions
Organisme : CIHR
Pays : Canada
Informations de copyright
© 2021 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons.
Références
Transplantation. 2016 Aug;100(8):1619-28
pubmed: 27140516
N Engl J Med. 2001 Mar 15;344(11):793-800
pubmed: 11248154
Glycoconj J. 1991 Oct;8(5):424-33
pubmed: 1841684
Transplantation. 2015 Nov;99(11):2364-71
pubmed: 25989497
PLoS One. 2015 Mar 25;10(3):e0119298
pubmed: 25807519
Ann Cardiothorac Surg. 2018 Jan;7(1):118-125
pubmed: 29492389
Transfusion. 2012 Apr;52(4):860-9
pubmed: 21981750
Transplant Proc. 1987 Feb;19(1 Pt 1):226-30
pubmed: 3547818
Am J Transplant. 2015 Oct;15(10):2602-15
pubmed: 26014598
Am J Kidney Dis. 2020 Nov;76(5):616-623
pubmed: 32668318
Nat Med. 2004 Nov;10(11):1227-33
pubmed: 15502841
Am J Transplant. 2016 May;16(5):1548-58
pubmed: 26602221
Glycobiology. 2015 Dec;25(12):1323-4
pubmed: 26543186
Transplantation. 2012 Mar 27;93(6):603-9
pubmed: 22290268
Transplantation. 2014 Nov 27;98(10):1089-96
pubmed: 24911035
Carbohydr Res. 2010 Nov 2;345(16):2305-22
pubmed: 20846641
Transplantation. 2015 Feb;99(2):e8-9
pubmed: 25651124
Biochim Biophys Acta. 2008 Feb;1780(2):75-88
pubmed: 18047841
J Biol Chem. 1990 Dec 5;265(34):20790-8
pubmed: 2249988
Arch Pathol Lab Med. 2008 Jul;132(7):1194-201
pubmed: 18605771
Transpl Int. 2005 Jan;17(11):666-72
pubmed: 15551052
Transplantation. 2014 Feb 15;97(3):e19-21
pubmed: 24492427
Transplantation. 2007 Dec 27;84(12 Suppl):S17-9
pubmed: 18162980
Am J Transplant. 2021 Nov;21(11):3649-3662
pubmed: 34101982
Transpl Int. 2015 Jan;28(1):25-33
pubmed: 25070762
Glycobiology. 2016 May;26(5):443-8
pubmed: 26755806
Vox Sang. 2016 Aug;111(2):161-70
pubmed: 27007982
Vox Sang. 1989;56(1):1-20
pubmed: 2464874
Curr Opin Organ Transplant. 2008 Apr;13(2):165-70
pubmed: 18685298
Carbohydr Res. 2011 Sep 6;346(12):1406-26
pubmed: 21531397
Nephrol Dial Transplant. 2011 Jul;26(7):2394-400
pubmed: 21558429
J Histochem Cytochem. 2008 Mar;56(3):223-31
pubmed: 17998569
Transplantation. 2006 Aug 27;82(4):479-85
pubmed: 16926591
Transfusion. 2016 Nov;56(11):2668-2679
pubmed: 27562458
Transfusion. 2012 Nov;52(11):2356-67
pubmed: 22587667