Precise oculocentric mapping of transcranial magnetic stimulation-evoked phosphenes.
Journal
Neuroreport
ISSN: 1473-558X
Titre abrégé: Neuroreport
Pays: England
ID NLM: 9100935
Informations de publication
Date de publication:
04 08 2021
04 08 2021
Historique:
pubmed:
9
6
2021
medline:
28
1
2022
entrez:
8
6
2021
Statut:
ppublish
Résumé
Transcranial magnetic stimulation (TMS)-evoked phosphenes are oculocentric; their perceived location depends upon eye position. We investigated the accuracy and precision of TMS-evoked phosphene oculocentric mapping. We evoked central phosphenes by stimulating early visual cortical areas with TMS, systematically examining the effect of eye position by asking participants to report the location of the evoked phosphene. We tested whether any systematic differences in the precision or accuracy of responses occurred as a function of eye position. Perceived phosphene locations map veridically to eye position, although there are considerable individual differences in the reliability of this mapping. Our results emphasize the need to carefully control eye movements when carrying out phosphene localization studies and suggest that individual differences in the reliability of the reported position of individual phosphenes must be considered.
Identifiants
pubmed: 34102648
doi: 10.1097/WNR.0000000000001683
pii: 00001756-202108010-00007
pmc: PMC8253501
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
913-917Subventions
Organisme : CIHR
ID : 390283
Pays : Canada
Informations de copyright
Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc.
Références
Meador KJ, Ray PG, Loring DW. Physiology of perception: parameters of TMS-induced phosphenes. Electroencephalogr Clin Neurophysiol. 1997; 102:P12
Salminen-Vaparanta N, Vanni S, Noreika V, Valiulis V, Móró L, Revonsuo A. Subjective characteristics of TMS-induced phosphenes originating in human V1 and V2. Cereb Cortex. 2014; 24:2751–2760
Schaeffner LF, Welchman AE. Mapping the visual brain areas susceptible to phosphene induction through brain stimulation. Exp Brain Res. 2017; 235:205–217
Mazzi C, Savazzi S, Abrahamyan A, Ruzzoli M. Reliability of TMS phosphene threshold estimation: Toward a standardized protocol. Brain Stimul. 2017; 10:609–617
Cowey A, Walsh V. Magnetically induced phosphenes in sighted, blind and blindsighted observers. Neuroreport. 2000; 11:3269–3273
Gothe J, Brandt SA, Irlbacher K, Röricht S, Sabel BA, Meyer BU. Changes in visual cortex excitability in blind subjects as demonstrated by transcranial magnetic stimulation. Brain. 2002; 125:479–490
Boroojerdi B, Bushara KO, Corwell B, Immisch I, Battaglia F, Muellbacher W, Cohen LG. Enhanced excitability of the human visual cortex induced by short-term light deprivation. Cereb Cortex. 2000; 10:529–534
Bestmann S, Ruff CC, Blakemore C, Driver J, Thilo KV. Spatial attention changes excitability of human visual cortex to direct stimulation. Curr Biol. 2007; 17:134–139
Brindley GS, Lewin WS. The sensations produced by electrical stimulation of the visual cortex. J Physiol. 1968; 196:479–493
Ong JM, da Cruz L. The bionic eye: a review. Clin Exp Ophthalmol. 2012; 40:6–17
Lewis PM, Ackland HM, Lowery AJ, Rosenfeld JV. Restoration of vision in blind individuals using bionic devices: a review with a focus on cortical visual prostheses. Brain Res. 2015; 1595:51–73
Dobelle WH, Mladejovsky MG. Phosphenes produced by electrical stimulation of human occipital cortex, and their application to the development of a prosthesis for the blind. J Physiol. 1974; 243:553–576
Tehovnik EJ, Slocum WM, Carvey CE, Schiller PH. Phosphene induction and the generation of saccadic eye movements by striate cortex. J Neurophysiol. 2005; 93:1–19
Niketeghad S, Pouratian N. Brain Machine Interfaces for Vision Restoration: The Current State of Cortical Visual Prosthetics. Neurotherapeutics. 2019; 16:134–143
Meyer BU, Diehl R, Steinmetz H, Britton TC, Benecke R. Magnetic stimuli applied over motor and visual cortex: influence of coil position and field polarity on motor responses, phosphenes, and eye movements. Electroencephalogr Clin Neurophysiol Suppl. 1991; 43:121–134
Peirce JW. Generating stimuli for neuroscience using PsychoPy. Front Neuroinform. 2008; 2:10
Peirce JW. PsychoPy-Psychophysics software in Python. J Neurosci Methods. 2007; 162813
Kammer T. Phosphenes and transient scotomas induced by magnetic stimulation of the occipital lobe: their topographic relationship. Neuropsychologia. 1999; 37:191–198